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Lysophosphatidylcholine suppresses apoptosis and induces neurite outgrowth in PC12 cells through activation of phospholipase D2

Yun DH, Jeon ES, Sung SM, Ryu SH, Kim JH

  • KMID: 1110121
  • Exp Mol Med.
  • 2006 Aug;38(4):375-384.
Lysophosphatidylcholine (LPC) is a bioactive lipid generated by phospholipase A2-mediated hydrolysis of phosphatidylcholine. In the present study, we demonstrate that LPC stimulates phospholipase D2 (PLD2) activity in rat pheochromocytoma PC12...
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