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BACKGROUND: Phospholipase C-beta4 (PLC-beta4) is known to be one of the most important signal transducing molecules; however, its biophysical and chemical characteristics are not well known due to the difficulty...
Yoo JM, Choi WS, Kim MO, Yoon HW, Park JM, Song JK
KMID: 2205015
J Korean Ophthalmol Soc.
1992 Dec;33(12):1194-1199.
In order to explore the existence and distribution of phospholipase (PLC) isozymes in the rat retina, immunohistochemical staining was applied using monoclonal antibodies against PLC isozymes (PLC beta; K92, PLC...
Rhyu IJ, Kim H, Kang YH, Park K, Hwang SJ, Suh PG, Suh YS
KMID: 2092655
Korean J Anat.
1998 Aug;31(4):535-544.
Phosphoinositide-specific phospholipase C(PLC) is known as a key enzyme which produces two major second messengers: diacylglycerol and inositol 1,4,5 trisphosphate. Although it has been suggested that PLC beta isozymes have...
BACKGROUND AND OBJECTIVES: A histological finding that is the most characteristic of cholesteatoma is the proliferation of the squamous cell. Signal transduction through phospholipase C(PLC) participates in the regulation of...
Park C, Han SH, Suh HK, Jung HH, Hwang SJ, Jung K, Lim HH
KMID: 2074345
Korean J Otolaryngol-Head Neck Surg.
1999 Feb;42(2):145-151.
BACKGROUND AND OBJECTIVES: Phosphoinositide specific phospholipase C (PLC) plays a pivotal role in the transmembrane signal transduction pathways by catalyzing the hydrolysis of phosphoinositide 4,5-bisphosphate (PIP2) to yield the intracellular...
We previously shown that LES contraction depends on M3 receptors linked to PTX insensitive Gq protein and activation of PLC. This results in production of IP3, which mediates calcium release,...