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1 PIK3CA Mutations in Hepatocellular Carcinoma in Korea

Kim H, Park CK, Lee SJ, Rha SY, Park KH, Lim HY

KMID: 2158221
Yonsei Med J.
2013 Jul;54(4):883-887.
doi: 10.3349/ymj.2013.54.4.883

PURPOSE: Phosphatidylinositol 3-kinases/AKT pathway plays a pivotal role in hepatocellular carcinoma (HCC). Mutant PIK3CA, encoding the p110a catalytic subunit, stimulates the AKT pathway and promotes cell growth in various cancers....

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