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1 Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid

Han S, Huh J, Kim W, Jeong S, Min DS, Jung Y

KMID: 2155391
Exp Mol Med.
2014 Dec;46(12):e126.
doi: 10.1038/emm.2014.86

Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is...

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