- Effect of brain angiotensin II receptor antagonists and antisense oligonucleotide on drinking and renal renin in rats
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Cho HK, Yang EK, Han HS, Lee WJ, Phillips M
- KMID: 1982600
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):137-142.
The physiological roles of brain angiotensin II in mediating water deprivation-induced drinking and in regulating renal renin release were assessed in male Sprague-Dawley rats. Specific AT1 receptor antagonists, losartan and SK 1080, and... -
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- Targeting Arginine-Dependent Cancers with Arginine-Degrading Enzymes: Opportunities and Challenges
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Phillips M, Sheaff MT, Szlosarek
- KMID: 2167635
- Cancer Res Treat.
- 2013 Dec;45(4):251-262.
Arginine deprivation is a novel antimetabolite strategy for the treatment of arginine-dependent cancers that exploits differential expression and regulation of key urea cycle enzymes. Several studies have focused on inactivation... -
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