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Taste Thresholds of Phenylthiocarbamide and 6-n-Propylthiouracil and their Correlation with TAS2R38 Genotype

Choi SY, Shin SH, Ye MK

BACKGROUND AND OBJECTIVES: Phenylthiocarbamide (PTC) and its chemically related compound,6-n-propylthiouracil (PROP), both produce a taste that is extremely bitter to some subjects (tasters) but tasteless or only slightly bitter to...
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Relationship between PTC Genotype and Taste Phenotype in Normal Volunteers

Ye MK, Shin TH

  • KMID: 2276971
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Dec;51(12):1124-1128.
BACKGROUND AND OBJECTIVES: The ability to taste the bitter compounds phenylthiocarbamide is a classic inherited trait in humans. This trait has also been shown to correlate with a number of...
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The Relationship between Single Nucleotide Polymorphisms of the Carbonic Anhydrase 6 Gene andPhenylthiocarbamide Taste Sensitivity, Taste Disorder

Bae JW, Kim UK, Oh SK, Rhyu MR, Shin SH, Ye MK

BACKGROUND AND OBJECTIVES: The phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taste sensitivity varies among individuals. Recently, it is reported that PROP taste responsiveness is associated with carbonic anhydrase 6 (CA6) gene...
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The Bitter Taste Receptor Agonist Quinine Reduces Calorie Intake and Increases the Postprandial Release of Cholecystokinin in Healthy Subjects

Andreozzi , Sarnelli G, Pesce M, Zito FP, D'Alessandro A, Verlezza V, Palumbo I, Turco F, Esposito K, Cuomo R

  • KMID: 2381299
  • J Neurogastroenterol Motil.
  • 2015 Oct;21(4):511-519.
  • doi: 10.5056/jnm15028
BACKGROUND/AIMS: Bitter taste receptors are expressed throughout the digestive tract. Data on animals have suggested these receptors are involved in the gut hormone release, but no data are available in...
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