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Molecular pharmacological interaction of phenylbutazone to human neutrophil elastase

Kang K

  • KMID: 1849847
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):385-393.
Human neutrophil elastase (HNElastase, EC 3.4.21.37), a causative factor of inflammatory diseases, was purified by Ultrogel AcA54 gel filtration and CM-Sephadex ion exchange chromatography. HNElastase was inhibited by phenylbutazone in a concentration dependent...
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Molecular characteristics of the inhibition of human neutrophil elastase by nonsteroidal antiinflammatory drugs

Kang K, Bae SJ, Kim WM, Lee DH, Cho US, Lee MS, Lee MH, Nam SI, Kuettner K, Schwartz D

  • KMID: 755079
  • Exp Mol Med.
  • 2000 Sep;32(3):146-154.
Nonsteroidal antiinflammatory drugs(NSAIDs) are known as clinically effective agents for treatment of inflammatory diseases. Inhibition of cyclooxygenase has been thought to be a major facet of the pharmacological mechanism of...
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Idiopathic Avascular Necrosis of the Femoral Head in Adults

Kim YM, Chang JK

Fifteen patients with idiopathic avascular necrosis of the femoral head who were admitted and treated in Department of Orthopedic Surgery, Seoul National University Hospital between January of 1965 and April...
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