- Failure to Produce Analgesia with Intramuscular Ketamine
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Kwon OK, Chon SU
- KMID: 2357574
- Korean J Anesthesiol.
- 1979 Jun;12(2):173-175.
Ketamine, a phencyclidine derivative, has been used as an anesthetic agent since 1965 and it has received much attention as an anesthetic for minor surgical procedures, in some diagnostic procedures... -
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- Effects of the Antioxidant Sulforaphane on Hyperlocomotion and Prepulse Inhibition Deficits in Mice after Phencyclidine Administration
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Shirai Y, Fujita Y, Hashimoto
- KMID: 2171215
- Clin Psychopharmacol Neurosci.
- 2012 Aug;10(2):94-98.
OBJECTIVE: Accumulating evidence suggests that oxidative stress plays a role in the pathophysiology of schizophrenia and that the potent antioxidants may be potential therapeutic drugs for schizophrenia. This study was... -
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- Rapid Changes in D1 and D2 Dopamine Receptor Binding in Striatal Subregions after a Single Dose of Phencyclidine
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Dalton VS, Zavitsanou K
- KMID: 2171262
- Clin Psychopharmacol Neurosci.
- 2011 Aug;9(2):67-72.
OBJECTIVE: In humans, a single exposure to phencyclidine (PCP) can induce a schizophrenia-like psychosis which can persist for up to two weeks. In rats, an acute dose of PCP increases... -
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- Clinical Use of CI-581, A New Intravenous or Intramuscular Anesthetic Agent
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Bae WS
- KMID: 1932477
- Korean J Anesthesiol.
- 1968 Jan;1(1):49-52.
CI-581(a phencyclidine derivative), a new potent, short-acting nonbarbiturate was administered to 101 patients, ranging in age from 2 months to 68 years, either intravenously, intramuscularly, or by a combination of... -
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- Effects of a New Antipsychotic Drug (YKP1447) on Impaired Prepulse Inhibition Induced by Apomorphine and Phencyclidine in Rats
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Yoon BS, Park EH, Park EH, Kwon JT, Hong SB, Dong SM, Kim YH, Heo J, Ji MK, Kim YG, Kwak BS, Choi JS, Kim HT
- KMID: 2287438
- Korean J Psychopharmacol.
- 2008 Jan;19(1):38-45.
OBJECTIVE: Schizophrenia, a devastating mental disorder, displays a wide range of cognitive impairments including attentional impairment. Prepulse inhibition (PPI), in which a startle response to a loud acoustic noise is... -
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- Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis
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Volf N, Hu G, Li M
- KMID: 1432539
- Clin Psychopharmacol Neurosci.
- 2012 Dec;10(3):168-179.
- doi: 10.9758/cpn.2012.10.3.168
OBJECTIVE: Iptakalim is a putative ATP-sensitive potassium (KATP) channel opener. It is also a novel nicotinic acetylcholine receptor (nAChR) blocker and can antagonize nicotine-induced increase in dopamine release in the... -
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- Experimental Models of Schizophrenia
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Cheon JS
- KMID: 2334614
- J Korean Soc Biol Psychiatry.
- 1999 Nov;6(2):153-160.
Animal models can provide a useful tool for the study of some aspects of psychiatric disorders and their treatment. The four criteria for the evaluation of animal models of psychiatric... -
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- The Effect of Ketamine on the Intestinal Motility of the Chicken
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Koh SO, Kim JR, Park KW, Kim WJ
- KMID: 2357565
- Korean J Anesthesiol.
- 1979 Jun;12(2):121-128.
In the late 1950, Greifenstein and associates have studied the properties of phenylcyelohexylamine derivatives and reported that these chemicals produced amnesia, analgesia, catatonia and catalepsy. Phencyclidine was the first of... -
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- The Vascular Effect of Ketamine Hydrochloride on The Isolated Rabbit Pulmonary ArteryC
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Lee SH, Suh JK, Chon SU
- KMID: 2240493
- Korean J Anesthesiol.
- 1994 Oct;27(10):1237-1245.
- doi: 10.4097/kjae.1994.27.10.1237
Ketamine hydrochloride is a phencyclidine derivatives and dissociative anesthetics. Ketamine induce the pulmonary vasoconetrietion in vivo. This study was designed to deter- mine the direct effect of the ketamine on... -
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