- Effect of Ketoconazole, a Cytochrome P450 Inhibitor, on the Efficacy of Quinine and Halofantrine against Schistosoma mansoni in Mice
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Seif el-Din SH, Sabra AN, Hammam OA, El-Lakkany NM
- KMID: 1499694
- Korean J Parasitol.
- 2013 Apr;51(2):165-175.
- doi: 10.3347/kjp.2013.51.2.165
The fear that schistosomes will become resistant to praziquantel (PZQ) motivates the search for alternatives to treat schistosomiasis. The antimalarials quinine (QN) and halofantrine (HF) possess moderate antischistosomal properties. The... -
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- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
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Wang Z, Jin H, Xu R, Mei Q, Fan D
- KMID: 1009393
- Exp Mol Med.
- 2009 Oct;41(10):717-727.
- doi: 10.3858/emm.2009.41.10.078
Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation... -
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