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Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles

Perrino BA

  • KMID: 2203574
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):213-225.
  • doi: 10.5056/jnm15186
An increase in intracellular Ca2+ is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca2+ sensitivity of the myofilaments by elevating myosin light chain phosphorylation...
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Responses to Enteric Motor Neurons in the Gastric Fundus of Mice With Reduced Intramuscular Interstitial Cells of Cajal

Sanders KM, Salter AK, Hennig GW, Koh SD, Perrino BA, Ward SM, Baker SA

  • KMID: 2381169
  • J Neurogastroenterol Motil.
  • 2014 Apr;20(2):171-184.
BACKGROUND/AIMS: Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pacemakers is well established, however their participation in neurotransmission...
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