- Identification of novel peptides that stimulate human neutrophils
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Bae GH, Lee HY, Jung YS, Shim JW, Kim SD, Baek SH, Kwon JY, Park JS, Bae YS
- KMID: 1120131
- Exp Mol Med.
- 2012 Feb;44(2):130-137.
- doi: 10.3858/emm.2012.44.2.008
Neutrophils play a key role in innate immunity, and the identification of new stimuli that stimulate neutrophil activity is a very important issue. In this study, we identified three novel... -
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- The Effect of Peripheral CRF Peptide and Water Avoidance Stress on Colonic and Gastric Transit in Guinea Pigs
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Hussain Z, Kim HW, Huh CW, Lee YJ, Park H
- KMID: 2419097
- Yonsei Med J.
- 2017 Jul;58(4):872-877.
- doi: 10.3349/ymj.2017.58.4.872
Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) diseases; however, there is frequent overlap between FD and IBS patients. Emerging evidence links the activation of corticotropin... -
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- Amyloid-beta oligomers regulate the properties of human neural stem cells through GSK-3beta signaling
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Lee IS, Jung K, Kim IS, Park KI
- KMID: 2154279
- Exp Mol Med.
- 2013 Nov;45(11):e60.
Alzheimer's disease (AD) is the most common cause of age-related dementia. The neuropathological hallmarks of AD include extracellular deposition of amyloid-beta peptides and neurofibrillary tangles that lead to intracellular hyperphosphorylated... -
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- Guanylyl cyclase C and guanylin reduce fat droplet accumulation in cattle mesenteric adipose tissue
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Yasuda M, Kawabata J, Akieda-Asai S, Nasu T, Date Y
- KMID: 2412452
- J Vet Sci.
- 2017 Sep;18(3):341-348.
- doi: 10.4142/jvs.2017.18.3.341
Guanylyl cyclase C (GC-C) is a member of a family of enzymes that metabolize GTP to cGMP and was first identified as a receptor for heat-stable enterotoxin. Guanylin (GNY) has... -
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- Anti-adenoviral Effects of Human Cationic Antimicrobial Protein-18/LL-37, an Antimicrobial Peptide, by Quantitative Polymerase Chain Reaction
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Uchio E, Inoue H, Kadonosono K
- KMID: 1798058
- Korean J Ophthalmol.
- 2013 Jun;27(3):199-203.
- doi: 10.3341/kjo.2013.27.3.199
PURPOSE: Antimicrobial peptides have an important role in self-protection of the ocular surface. Human cationic antimicrobial protein (hCAP)-18 is a linear, alpha-helical peptide that consists of a conserved pro-sequence called... -
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- Exendin-4 Protects Oxidative Stress-Induced beta-Cell Apoptosis through Reduced JNK and GSK3beta Activity
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Kim JY, Lim DM, Moon CI, Jo KJ, Lee SK, Baik HW, Lee KH, Lee KW, Park KY, Kim BJ
- KMID: 1779233
- J Korean Med Sci.
- 2010 Nov;25(11):1626-1632.
- doi: 10.3346/jkms.2010.25.11.1626
Oxidative stress induced by chronic hyperglycemia in type 2 diabetes plays a crucial role in progressive loss of beta-cell mass through beta-cell apoptosis. Glucagon like peptide-1 (GLP-1) has effects on... -
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- GD3 Accumulation in Cell Surface Lipid Rafts Prior to Mitochondrial Targeting Contributes to Amyloid-beta-induced Apoptosis
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Kim JK, Kim SH, Cho HY, Shin HS, Sung HR, Jung JR, Quan ML, Jiang DH, Bae HR
- KMID: 2157855
- J Korean Med Sci.
- 2010 Oct;25(10):1492-1498.
- doi: 10.3346/jkms.2010.25.10.1492
Neuronal apoptosis induced by amyloid beta-peptide (A beta) plays an important role in the pathophysiology of Alzheimer's disease (AD). However, the molecular mechanism underlying A beta-induced apoptosis remains undetermined. The... -
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- LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils
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Lee HY, Kim SD, Shim JW, Lee SY, Yun J, Bae YS
- KMID: 1123806
- Exp Mol Med.
- 2009 May;41(5):325-333.
- doi: 10.3858/emm.2009.41.5.036
Serum amyloid A (SAA) has been regarded as an important mediator of inflammatory responses. The effect of several formyl peptide receptor-like 1 (FPRL1) ligands on the production of IL-8 by... -
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