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A Nationwide Cohort Study Shows a Sex-Dependent Change in the Trend of Peptic Ulcer Bleeding Incidence in Korea between 2006 and 2015

Kim YS, Lee J, Shin A, Lee JM, Park JH, Jung HY

Background/Aims: The incidence of peptic ulcer disease has decreased in past decades; however, the trends in peptic ulcer bleeding (PUB) are inconsistent among regions. This study aimed to investigate the...
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Needle or knife? The role of interventional radiology in managing uncontrolled gastrointestinal bleeding

Background: Increasingly interventional radiology has been used to stop uncontrolled gastrointestinal (GI) bleeding leading to a reduction in the requirement for surgical intervention. To examine the safety and efficacy of...
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Management of Peptic Ulcer Bleeding in Patients Taking Aspirin or Anticoagulant

Yang HJ

Antiplatelet and anticoagulation agents are increasingly prescribed for secondary prophylaxis in patients with cardiovascular and cerebrovascular diseases. These drugs are associated with an increased risk of gastrointestinal bleeding, including peptic...
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Massive Duodenal Bleeding after the Migration of Endovascular Coils into the Small Bowel

Choi CJ, Lim H, Kim DS, Jeong YS, Park SY, Kim JE

Among gastrointestinal emergencies, acute upper gastrointestinal bleeding remains a challenging clinical problem owing to significant patient morbidity and costs involved in management. Endoscopic hemostatic therapy is the mainstay of treatment...
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Factors Associated with Rebleeding in Patients with Peptic Ulcer Bleeding: Analysis of the Korean Peptic Ulcer Bleeding (K-PUB) Study

Kim JS, Kim BW, Park SM, Shim KN, Jeon SW, Kim SW, Lee YC, Moon HS, Lee SH, Jung WT, Kim JI, Kim KO, Park JJ, Chung WC, Kim JH, Baik GH, Oh JH, Kim SM, Kim HS, Yang CH, Jung JT, Lim CH, Song HJ, Kim YS, Kim GH, Kim JH, Chung JI, Lee JH, Choi MH, Choi JK

BACKGROUND/AIMS: Rebleeding is associated with mortality in patients with peptic ulcer bleeding (PUB), and risk stratification is important for the management of these patients. The purpose of our study was...
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Endoscopic Hemostatic Treatment of Peptic Ulcer Bleeding

Choe YH, Park JC

Peptic ulcer bleeding is a common complication of peptic ulcer disease and the most common cause of upper gastrointestinal bleeding. Despite advances in drug usage and endoscopic modalities, no significant...
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Recent Developments in the Endoscopic Treatment of Patients with Peptic Ulcer Bleeding

Jang JY

Peptic ulcer bleeding is an internal medical emergency. Endoscopic hemostasis has been shown to improve the survival rate of patients with peptic ulcer bleeding. Although the established hemostatic modalities, including...
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Optimal Operational Definition of Patient with Peptic Ulcer Bleeding for Big Data Analysis Using Combination of Clinical Characteristics in a Secondary General Hospital

Lee JW, Kim HK, Woo YS, Jahng J, Jin YR, Park JH, Kim YS, Jung HY

BACKGROUND/AIMS: Peptic ulcer bleeding (PUB) is the most common cause of upper gastrointestinal bleeding in Korea but there has been no research done using big data. This study evaluates the...
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Helicobacter pylori Eradication within 120 Days Is Associated with Decreased Complicated Recurrent Peptic Ulcers in Peptic Ulcer Bleeding Patients

Chang SS, Hu HY

BACKGROUND/AIMS: The connection between Helicobacter pylori and complicated peptic ulcer disease in peptic ulcer bleeding (PUB) patients taking nonsteroidal anti-inflammatory drugs has not been established. In this study, we sought...
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Diagnosis and Management of Peptic Ulcer Bleeding

Sung JK

Despite the generally declining trend in the incidence of peptic ulcers, peptic ulcer bleeding remains a prevalent and clinically significant condition. Additionally, despite the development of therapeutic endoscopy and acid-suppressive...
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Complications and Management of Peptic Ulcer Disease

Bang CS, Baik GH

Despite the improvement of medical managements of peptic ulcer and decline of Helicobacter pylori infection, complications of peptic ulcer are still prevalent in clinical practice. This is because of the...
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Pharmacological Therapy of Peptic Ulcer

Oh JH

Peptic ulcer disease is one of the most commonly encountered diseases. Despite the decrease of Helicobacter pylori infection, the use of aspirin and non-steroidal anti-inflammatory drugs has increased in recent...
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Management of Non-Variceal Upper Gastrointestinal Bleeding

Kim SY, Hyun JJ, Jung SW, Lee SW

  • KMID: 2134511
  • Clin Endosc.
  • 2012 Sep;45(3):220-223.
Upper gastrointestinal bleeding (UGIB) is a critical condition that demands a quick and effective medical management. Non-variceal UGIB, especially peptic ulcer bleeding is the most significant cause. Appropriate assessment and...
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Gastric Submucosal Hematoma after Endoscopic Hemostasis in Patient with Dual Antiplatelet Therapy

Kim T, Kim HU, Song HJ

Intramural hematoma of the gastrointestinal tract is uncommon, with the majority being localized to the esophagus or duodenum. Hematoma of the gastric wall is extremely rare and caused by coagulopathy,...
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A Comparison of the Effect of High-dose Oral and Intravenous Proton Pump Inhibitor on the Prevention of Rebleeding after Endoscopic Treatment of Bleeding Peptic Ulcers

Jang JY, Joo KR, Hwangbo Y, Jeong LI, Choi SY, Jung JH, Chae MJ, Lee SK, Dong SH, Kim HJ, Kim BH, Chang YW, Lee JI, Chang R

  • KMID: 2304841
  • Korean J Gastrointest Endosc.
  • 2006 Jul;33(1):6-11.
BACKGROUND/AIMS: The use of proton pump inhibitor (PPI) prevents rebleeding by elevating the intragastric pH in patients with bleeding peptic ulcers after hemostasis has been achieved. We assessed if high-dose...
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Efficacy of ethanol and hypertonic saline-epinephrine injection therapy for peptic ulcer bleeding

Ahn JY, Kim JG, Kim JW, Kim SJ, Han SP, Kim HJ, Do JH, Chang SK, Park SM

  • KMID: 1984638
  • Korean J Med.
  • 2005 Jul;69(1):21-29.
BACKGROUND: One of simple, inexpensive, readily available treatments for treating peptic ulcer bleeding is injection of the lesion with a sclerosing substance such as ethanol and hypertonic saline-epinephrine. The aim...
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Risk Factors for Rebleeding after Initial Endoscopic Hemostasis in Patients with Peptic Ulcer Hemorrhage

Joo SY, Joo YE, Noh DY, Park SY, Lee WS, Park CH, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

  • KMID: 1973361
  • Chonnam Med J.
  • 2004 Jun;40(2):79-86.
Rebleeding after initial endoscopic hemostasis in patients with peptic ulcer hemorrhage has been reported in 20~30%. Identification of patients who are at high risk for rebleeding would be expected to...
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