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The Natural History of Peyronie’s Disease

Maida FD, Cito G, Lambertini L, Valastro F, Morelli G, Mari A, Carini M, Minervini A, Cocci A

Peyronie’s disease (PD), a fibrotic disorder of the tunica albuginea fully described in 1793 by French physician Francois de la Peyronie, is characterized by pain, plaque formation, penile deformity, and...
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Walking-Evoked Erection in Patients with Lumbar Degenerative Diseases: Eight Cases and Review of the Literature

Hirota K, Hanakita J, Takahashi T, Kanematsu R, Ueno M, Kasuya H, Minami M

Study Design: Narrative review with a case illustration. Purpose: The purpose of this study was to evaluate the pathogenesis and outcome of therapy for walking-evoked erection in patients with lumbar degenerative...
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A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Therapeutic Confirmatory Study to Evaluate the Safety and Efficacy of Avanafil in Korean Patients with Erectile Dysfunction

Park HJ, Kim SW, Kim JJ, Lee SW, Paick JS, Ahn TY, Park K, Park JK, Park NC

A multi-center, randomized, double-blind, placebo-controlled study was conducted with 158 subjects who were randomized to placebo or avanafil 50, 100, and 200 mg on demand for 8 weeks to evaluate...
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The Effect of Alcohol Administration on the Corpus Cavernosum

Choi SM, Seo DH, Lee SW, Lee C, Jeh SU, Kam SC, Hwa JS, Chung KH, Hyun JS

PURPOSE: We studied the effects of alcohol administration on the corpus cavernosum (CC) using an animal model. MATERIALS AND METHODS: CC sections and the aortic ring of rabbits were used in...
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Clinical Management of Priapism: A Review

Shigehara , Namiki M

Priapism is defined as a persistent and painful erection lasting longer than four hours without sexual stimulation. Based on episode history and pathophysiology, priapism is classified into three subtypes: ischemic...
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Clinical Neuroanatomy and Neurotransmitter-Mediated Regulation of Penile Erection

Jung J, Jo HW, Kwon H, Jeong NY

  • KMID: 2232925
  • Int Neurourol J.
  • 2014 Jun;18(2):58-62.
Erectile dysfunction (ED) has an adverse impact on men's quality of life. Penile erection, which is regulated by nerves that are innervated into the erectile tissue, can be affected by...
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Efficacy of Long-Term Daily Dosage of Alfuzosin 10 mg upon Sexual Function of Benign Prostatic Hypertrophy Patients: Two-Year Prospective Observational Study

Yoon S, Choi JH, Lee SH, Choi SM, Jeh SU, Kam SC, Hwa JS, Chung KH, Hyun JS

PURPOSE: To identify sexual function improvement associated with alfuzosin (10 mg daily for 2 years). MATERIALS AND METHODS: We enrolled 30 men with lower urinary tract symptom (LUTS) who visited Gyeongsang...
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Transient Distal Penile Corporoglanular Shunt as an Adjunct to Aspiration and Irrigation Procedures in the Treatment of Early Ischemic Priapism

Canguven O, Cetinel C, Horuz R, Tarhan F, Hamarat B, Goktas C

  • KMID: 2316018
  • Korean J Urol.
  • 2013 Jun;54(6):394-398.
PURPOSE: Ischemic priapism, a compartment syndrome, requires urgent treatment in order to nourish the corpora cavernosa. As the first step, aspiration of blood and irrigation of the cavernosal bodies is...
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Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection

Do J, Choi S, Choi J, Hyun JS

  • KMID: 2430620
  • Korean J Urol.
  • 2013 Mar;54(3):183-188.
PURPOSE: Tribulus terrestris has been used as an aphrodisiac. However, little is known about the effects and mechanism of action of T. terrestris on penile erection. Therefore, the effect of...
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Isolation and Characterization of Smooth Muscle Cells from Rat Corpus Cavernosum Tissue for the Study of Erectile Dysfunction

Chung H, Jung SH, Ryu JK, Kim B, Kim HS, Yang SK

  • KMID: 2315598
  • Korean J Urol.
  • 2012 Aug;53(8):556-563.
PURPOSE: Primary culture of the cavernous smooth muscle cells from corpus cavernous tissues is known to be difficult, mainly because of contamination with fibroblasts. We applied a new method for...
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The Effects of New Herbal Formula (KBMSI-1) on the Penile Erection and Corpus Cavernosum in Streptozotocin-induced Diabetic Rats

Yoon BI, Shin TS, Woo JC, Kim SJ, Kim HS, Ha US, Kim HJ, Hwang SY, Kim SW

PURPOSE: The aim of this study was to investigate the effects of new herbal formula (KBMSI-1) on erectile dysfunction in streptozotocin-induced diabetic rat model. MATERIALS AND METHODS: We used male Sprague-Dawley...
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Direct Effect of Carbon Monoxide on Relaxation Induced by Electrical Field Stimulation in Rat Corpus Cavernosum

Kim DW, Zhao C, Kim MK, Park JK

PURPOSE: Carbon monoxide (CO) may mediate smooth muscle relaxation in the rat corpus cavernosum smooth muscle (CCSM). We hypothesized that CO plays a role in neurally derived, frequency-dependent relaxation of...
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Assessment of Erectile and Ejaculatory Function after Penile Prosthesis Implantation

Bae JH, Song PH, Kim HT, Moon KH

  • KMID: 2314696
  • Korean J Urol.
  • 2010 Mar;51(3):202-207.
PURPOSE: We investigated erectile and ejaculatory function after penile prosthesis implantation. MATERIALS AND METHODS: A total of 121 patients were enrolled in the surgery group (SG) and 120 patients in...
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Penile Erection during Transurethral Surgery : Case report and review of the literature

Won YJ, Hong JY

  • KMID: 1741600
  • Anesth Pain Med.
  • 2008 Apr;3(2):154-156.
Imbalance between sympathetic and parasympathetic nervous systems is generally considered an underlying mechanism for intraoperative erection, although local stimulation before complete sensory blockade can contribute to the problem. With the...
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High Flow Priapism Developed after Treatment of Low Flow Priapism

Kim JH, Choi HJ, Ryu KH, Jeong YS, Choi YS, Lee SW

  • KMID: 2294040
  • Korean J Urol.
  • 2005 Aug;46(8):876-878.
Priapism is a pathologic state of persistent penile erection in the absence of sexual stimulation. Low flow priapism is more common, which is caused by a venous outflow obstruction. However,...
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Anesthetic Management of the Patient with Persistent Penile Erection Developed after Spinal Anesthesia: A case report

Go JE, Sohn JT, Kim HJ, Shin IW, Lee HK, Chung YK

A 50-year-old man with bladder cancer had spinal anesthesia for transurethral resection of bladder. After he had spinal block at the T8 level, he developed a persistent penile erection, making...
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Cerebral Proerectile Effect of Apomorphine and Vasoactive Agents in Anesthetized Rats

Yan BQ, Park HJ, Park NC

  • KMID: 1764827
  • Korean J Urol.
  • 2004 Mar;45(3):274-282.
PURPOSE: To establish central control of a penile erection, the centrally elicited erectile effects of apomorphine hydrochloride and various vasoactive agents were investigated after intracerebroventricular administration. MATERIALS AND METHODS: Anesthetized male...
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Drug Induced Cerebral Proerectile Effect in Anesthethetized Rats

Park HJ, Nam JK, Park NC

  • KMID: 2298601
  • Korean J Androl.
  • 2004 Dec;22(3):132-140.
PURPOSE: To examine the centrally elicited erectile effects of alpha-MSH, oxytocin, prostagladin E1, and anabolic steroids after intracerebroventricular administration. MATERIALS AND METHODS: We used anesthetized male Sprague-Dawley rats. After intracerebroventricular...
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Intracavernosal Injection of Insulin Like Growth Factor-1 Improves Erectile Function in Aging Rat

Ahn KY, Park K, Oh KJ, Kim MK, Lee SE, Lee YI, Ryu SB

  • KMID: 2298599
  • Korean J Androl.
  • 2004 Dec;22(3):118-123.
PURPOSE: Insulin like growth factor-1 (IGF-1) is known to promote the proliferation and migration of penile cavernous smooth muscle cells in rat. The purpose of this study was to investigate...
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A Synergistic Effect of Apomorphine on Sildenafil Induced Penile Erection in Conscious Rabbits

Park JY, Son HC, Paick JS

  • KMID: 2293336
  • Korean J Urol.
  • 2003 May;44(5):452-459.
PURPOSE: The aim of this study was to demonstrate that the combined systemic administration of apomorphine (APO) and sildenafil have a synergistic effect on the erection in conscious rabbits. MATERIALS...
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