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Adenovirus Expressing Human Interferon Inhibits Replication of Foot and Mouth Disease Virus and Reduces Fatal Rate in Mice

Chu JQ, Kim SM, Lee KN, Oem JK, Ko YJ, Lee HS, Kim YJ, Park JY, Kim KJ, Parida S, Oh Y, Paton DJ, Joo YS, Kim B, Park JH

Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-alpha (Ad-HIFNalpha) or pig interferon-beta fused with...
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