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PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy

Guo S, Loibl S, von Minckwitz G, Darb-Esfahani S, Lederer B, Denkert C

Purpose PIK3CA, encoding for subunit p110a of phosphatidylinositol 3 kinase, is frequently mutated in breast cancer. PIK3CAmutation was predictive for pathological complete response (pCR) in human epidermal growth factor 2 positive...
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Response Assessment with MRI after Chemoradiotherapy in Rectal Cancer: Current Evidences

Seo N, Kim H, Cho MS, Lim JS

Baseline magnetic resonance imaging (MRI) has become the primary staging modality for surgical plans and stratification of patient populations for more efficient neoadjuvant treatment. Patients who exhibit a complete response...
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