- Presynaptic Dysfunction by Familial Factors in Parkinson Disease
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Lee W, Koh S, Hwang S, Kim SH
- KMID: 2426689
- Int Neurourol J.
- 2018 Oct;22(Suppl 3):S115-S121.
- doi: 10.5213/inj.1836216.108
Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer disease. The loss of specific brain area, the substantia nigra pars compacta is known as a major etiology,... -
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- Non-Motor Symptom Burdens Are Not Associated with Iron Accumulation in Early Parkinson's Disease: a Quantitative Susceptibility Mapping Study
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Shin C, Lee S, Lee JY, Rhim JH, Park SW
- KMID: 2409209
- J Korean Med Sci.
- 2018 Mar;33(13):e96.
- doi: 10.3346/jkms.2018.33.e96
BACKGROUND: Quantitative susceptibility mapping (QSM) has been used to measure iron accumulation in the deep nuclei of patients with Parkinson's disease (PD). This study examined the relationship between non-motor symptoms... -
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- Astrocyte Specificity and Coverage of hGFAP-CreERT2 [Tg(GFAP-Cre/ERT2)13Kdmc] Mouse Line in Various Brain Regions
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Park YM, Chun H, Shin JI, Lee CJ
- KMID: 2430108
- Exp Neurobiol.
- 2018 Dec;27(6):508-525.
- doi: 10.5607/en.2018.27.6.508
Astrocyte is the most abundant cell type in the central nervous system and its importance has been increasingly recognized in the brain pathophysiology. To study in vivo function of astrocyte,... -
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- Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson's Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways
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Park JS, Leem YH, Park JE, Kim DY, Kim HS
- KMID: 2442009
- Biomol Ther.
- 2019 Feb;27(2):178-184.
- doi: 10.4062/biomolther.2018.234
Parkinson's disease is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta. In the present study, we investigated whether β-Lapachone (β-LAP), a... -
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- Delayed Treatment of Capsaicin Produces Partial Motor Recovery by Enhancing Dopamine Function in MPPâº-lesioned Rats via Ciliary Neurotrophic Factor
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Kim KI, Baek JY, Jeong JY, Nam JH, Park ES, Bok E, Shin WH, Chung YC, Jin BK
- KMID: 2450220
- Exp Neurobiol.
- 2019 Apr;28(2):289-299.
- doi: 10.5607/en.2019.28.2.289
Transient receptor potential vanilloid subtype 1 (TRPV1) on astrocytes prevents ongoing degeneration of nigrostriatal dopamine (DA) neurons in MPPâº-lesioned rats via ciliary neurotrophic factor (CNTF). The present study determined whether... -
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