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Transcriptional mutagenesis by 8-oxodG in alpha-synuclein aggregation and the pathogenesis of Parkinson's disease

Basu S, Je G, Kim YS

Parkinson's disease (PD) is an age-related progressive neurodegenerative disease associated with selective loss of dopaminergic neurons. The characteristic hallmark of the disease is intracytoplasmic proteinacious inclusion bodies called Lewy bodies,...
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Association of Vitamin D Receptor Gene Polymorphism and Parkinson's Disease in Koreans

Kim JS, Kim YI, Song C, Yoon I, Park JW, Choi YB, Kim HT, Lee KS

1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3), which is the biologically active form of vitamin D, has anti-inflammatory effects and can prevent experimental Parkinson's disease (PD). 1,25(OH)2D3 exerts most of its actions only after...
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