- Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers
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Park S, Hyun YJ, Kim YR, Lee JH, Ryu S, Kim JM, Oh WY, Na HS, Lee JG, Seo DW, Hwang IY, Park Z, Jang IJ, Oh J, Choi SE
- KMID: 2375071
- J Korean Med Sci.
- 2017 May;32(5):729-736.
- doi: 10.3346/jkms.2017.32.5.729
The aim of this study was to examine the effects of CYP2C19*2 and *3 genetic polymorphisms on omeprazole pharmacokinetic (PK) and pharmacodynamic (PD) responses. Twenty-four healthy Korean volunteers were enrolled... -
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- Influence of CYP2D6 Polymorphism on the Pharmacokinetic/Pharmacodynamic Characteristics of Carvedilol in Healthy Korean Volunteers
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Jung E, Ryu S, Park Z, Lee JG, Yi JY, Seo DW, Lee J, Jeong HS, Kim JM, Oh WY
- KMID: 2414573
- J Korean Med Sci.
- 2018 Jul;33(27):e182.
- doi: 10.3346/jkms.2018.33.e182
BACKGROUND: Carvedilol is commonly used to treat hypertension as a β- and α1-adrenoreceptor blocker, but it is metabolized by CYP2D6, and CYP2D6*10 allele is dominant in Asian population. The objective... -
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- Citation Analysis for Biomedical and Health Sciences Journals Published in Korea
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Oh J, Chang H, Kim JA, Choi M, Park Z, Cho Y, Lee EG
- KMID: 2403312
- Healthc Inform Res.
- 2017 Jul;23(3):218-225.
- doi: 10.4258/hir.2017.23.3.218
OBJECTIVES: A citation analysis of biomedical and health sciences journals was conducted based on their enlistment in journal databases to identify the factors contributing to the citation metrics. METHODS: Among the... -
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