- Bacterial Lipopolysaccharide - Induced Generation of Nitric Oxide is Mediated by ERK1 and JNK1 / SAPK in Primary Rat Neonatal Astrocytes
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Kim MS, Lee KM, Park RK
- KMID: 1572924
- Korean J Immunol.
- 2000 Mar;22(1):1-8.
No abstract available. -
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- Interaction of FcalphaR with gamma Subunit of FcgammaRIalpha to Modulate Cbl, Shc and Grb2 Adaptor Proteins
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Chung HT, Park RK
- KMID: 1548222
- Korean J Immunol.
- 1997 Jun;19(2):209-218.
No abstract available. -
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- Roles of Nitric Oxide and Tumor Necrosis Factor in Liver Inloammation Induced by C . parvum and LPS
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Yoo JC, Pae HO, Chung HT, Jun CD, Kim YH, Kim SM, Park RK, Jin HS
- KMID: 1192678
- Korean J Immunol.
- 1998 Jun;20(2):237-243.
No abstract available. -
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- Involvement of Fibronectin in the Migration of Macrophage and Expression of Nitric Oxide Synthase in the BCG induced Inflammatory Sites in Rat Bladder
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Chung HT, Jun CD, Kwak HJ, Rim JS, Yu JC, Park RK, Park JH, Pai HO
- KMID: 1548374
- Korean J Immunol.
- 1997 Dec;19(4):493-504.
No abstract available. -
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- The Effect of Protein Kinase C Pretreatment on Gliotoxin Induced Apoptosis in H9c2 Cells
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Her JM, Oh JM, Park RK, So HS, Mun YJ, Choi MK, Lee GS, Chung YT, Park OK
- KMID: 1578399
- Korean J Phys Anthropol.
- 2000 Mar;13(1):119-128.
Aspergillus funigatus and other pathogenic fungi synthesize a toxic epidithi- odiopiperzine (ETP) metabolite called gliotoxin. Gliotoxin is an epidithiodiopiperzine compound which can both react with sulfhydryl groups and form hydrogen... -
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- Effect of Nitric Oxide on the Viability of Bone Marrow - Derived Cultured Mast Cells
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Chung HT, Park RK, Jun CD, Choi BM, Lee SJ
- KMID: 1548384
- Korean J Immunol.
- 1997 Dec;19(4):595-600.
It is well established that mast cell proliferation and maturation are regulated by two principle cytokines, IL-3 and the c-kit ligand stem cell factor (SCF). Previous reports have demonstrated that... -
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- Effects of Taxol on the Synthesis of Nitric Oxide in Murine Microglial Cells
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Chung HT, Park RK, Jun CD, Kwak HJ, Yoo JC, Pae HO, Song JH
- KMID: 2083004
- Korean J Immunol.
- 1997 Sep;19(3):383-390.
Taxol, an anticancer drug, blocks cell division by stabilizing microtubules. However, taxol has distinct cell-cycle-independent effects. For example, taxol and bacterial LPS induce strikingly similar responses in murine microglial cells.... -
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- Flow Cytometric Analysis of T-cell Subsets in Brain Tumor Patients
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Nam J, Kim HI, Lee JC, Park RK, Chung HT
- KMID: 2187674
- J Korean Neurosurg Soc.
- 1989 Dec;18(7-12):977-984.
The immunocompetence is important not only to kill the neoplastic cells but also to keep the neoplastic cells from growing further. T lymphocyte is plays the most important role in... -
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- Protective Effect of PKC Affecting Taxol-induced Cytotoxicity in MCF-7 Cells
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Oh JM, Jung KM, Bang HJ, So HS, Park RK, Kim JJ, Choi MK, Park ST, Chung YT
- KMID: 2224545
- Korean J Anat.
- 2000 Oct;33(5):571-578.
Paclitaxel (taxol) is known as effective drug inhibition of cell cycle encouraging activity in human ovarian and metastatic breast cancers and malignant melanoma. It is an antimicrotubule agent that is... -
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- Gliotoxin induces the Apoptosis in HL-60 Cells
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Chung HT, Park RK, Choi YK, Lee SR, Kim YH, Cho KH, Jang YW
- KMID: 1557245
- Korean J Immunol.
- 1998 Dec;20(4):397-403.
Many fungi including Penicillium, Aspergillus, Gliocladium, and Thermoascus produce an epipolythiodioxopiperazine class of fungal metabolite, gliotoxin, which contirbutes the pathogenesis of fungal infection as an immunomodulator and cytotoxic agent. This... -
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- Characteristics of the Molecular Interaction of Adaptor Proteins in Protein Tyrosine Kinase Cascades
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Park YK, Choi SJ, Park RK, Chung SY, Kim SK
- KMID: 2048558
- Chonnam Med J.
- 1998 Dec;34(2):157-176.
Recent evidence suggests that FcgammaR and FcgammaR receptors signal through the low molecular weight GTPase, Ras. Ras is regulated by the nucleotide exchange protein, Sos, via formation of Grb2/Sos complex.... -
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- Signaling Pathway of the Bacterial Lipopolysaccharide-induced Generation of Nitric Oxide in Rat Primary Astorcytes
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Kwang S, Park RK, Lee SY, Park MC
- KMID: 2340348
- J Korean Neuropsychiatr Assoc.
- 1999 Jul;38(4):881-893.
OBJECTIVES: Nitric oxide(NO)plays an important role in pathophysiology of stroke and various neurodegenerative diseases. This study is designed to elucidate the mechanisms by which signaling pathway of LPS-stimulated NO... -
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- Impact of Nucleotide Mutations at the HNF3- and HNF4-Binding Sites in Enhancer 1 on Viral Replication in Patients with Chronic Hepatitis B Virus Infection
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Cho EY, Kim HJ, Park C, So HS, Park RK, Kim HC
- KMID: 1806674
- Gut Liver.
- 2013 Sep;7(5):569-575.
BACKGROUND/AIMS: The hepatitis B virus (HBV) genome contains binding sites for hepatocyte nuclear factors (HNF) 3 and 4 in the core domain of enhancer 1 (Enh1), and mutations in this... -
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- Comparison of bare metal stent and paclitaxel-eluting stent using a novel rat aorta stent model
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Kwon JS, Park RK, Shim TJ, Jeong MH, Cho MC, Ahn Y, Kim DW
- KMID: 1106556
- J Vet Sci.
- 2011 Jun;12(2):143-149.
- doi: 10.4142/jvs.2011.12.2.143
The purpose of our study was to create a novel rat aorta stent implantation model. Stainless steel bare metal stents (BMS) or paclitaxel-eluting stents (PES) were implanted in male Sprague-Dawley... -
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- Study of Hydroxyurea Induced Caspase Activities in Chronic Myelogenous Leukemic Cell Line, K562 cells
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Lee YJ, Park RK, So HS, Park JS, Cho JH, Choi SI
- KMID: 2225957
- Korean J Clin Pathol.
- 2000 Oct;20(5):435-441.
BACKGROUND: Chronic myelogenous leukemia is a chronic myeloproliferative disorder characterized by leukocytosis with myeloid elements at all stages of differentiation, t(9;22)(q34;q11) and bcr/abl rearrangement. We studied hydroxyurea induced apoptotic changes... -
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- Step-by-step Management and Treatment Outcome of Bleeding Control for Anastomosis Site after Low Anterior Resection with Double Stapling Technique
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Kim HM, Shin EJ, Song OP, Kim JJ, Jang YS, Park RK, Baek MJ
- KMID: 2334334
- J Korean Soc Coloproctol.
- 2005 Dec;21(6):390-395.
PURPOSE: This study reviews our experience with a step- by-step management approach of increasing aggressiveness and evaluates the treatment outcome for intraluminal hemorrhage. METHODS: The study group was comprised of patients... -
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- Bacterial Endotoxin, Lipopolysaccaride, and Induced Activation of Stress-Activated Protein Kinase and Generation of Nitric Oxide
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Choi SJ, Lee YS, Park RK, Chung SY, Kim SK
- KMID: 2206461
- J Korean Surg Soc.
- 1999 Apr;56(4):468-478.
BACKGROUND: Previously, it has been suggested that lipopolysaccaride (LPS) stimulates the activation of the transcriptional factor activator protein (AP-1) which is in part regulated by activation of the c-Jun N-terminal... -
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- Comparison of Biological and Genetic Characteristics Between Sucrose-Fermenting and Sucrose-Nonfermenting Vibrio vulnificus Isolates
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Kim SM, So HA, Song KM, Lee YY, Lim CW, Lee JH, So HS, Kim JK, Park RK, Park SD
- KMID: 2055030
- J Bacteriol Virol.
- 2006 Dec;36(4):221-228.
- doi: 10.4167/jbv.2006.36.4.221
Twelve strains of V. vulnificus isolated from clinical specimens in 2002~2004 in Jeollado province were determined for their biologic groups, serotypes, presence of vvhA (hemolysin/cytolysin) gene, DNA sequence, and PFGE... -
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- The Effects of Divalant Cation on the Idarubicin-Induced Apoptosis
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Choi DY, Oh MT, Oh YG, Kim JD, Park RK
- KMID: 1979929
- Korean J Pediatr Hematol Oncol.
- 2000 Apr;7(1):105-114.
PURPOSE: Zinc ion is critical for the functional and structural integrity of eukaryotic cells and participate in the regulation of apoptosis. In general, zinc inhibits a nuclear endonuclease, thereby... -
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- Radiation-induced Apoptotic Signaling Pathway in HL - 60 Cells
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Ahn SJ, Park RK, Lee SR, Chung WK, Nah BS, Nam TK, Chung HT, Moon SR, Kang HK, Park SJ
- KMID: 2137123
- J Korean Cancer Assoc.
- 2000 Feb;32(1):156-167.
PURPOSE: The mechanical insights of death of cancer cells by ionizing radiation are not yet clearly defined. Recent evidences have demonstrated that radiation therapy may induce cell death via activation of signaling pathway... -
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