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Proteome identification of common immunological proteins of two nematode parasites

Kang SA, Yu HS

Although helminth parasites have different life cycles, their hosts share similar immune responses involving Th2 cell-type. Here, we extracted proteins from the larvae of Anisakis simplex complex and Trichinella spiralis...
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Sparganosis in the Indian Sub-continent and the Middle East

Nawa Y, Tanaka M, Yoshikawa M

Sparganosis is one of the common zoonotic diseases caused by infection with the larval plerocercoids (spargana) of the cestode genus Spirometra. While this parasite distributes globally in canine and feline...
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A novel kit for enrichment of fecal helminth eggs

Lee E, Back SO, Lee YJ, Ju JW, Lee HI, Lee MR

We developed a new concentration kit, called the ParaEgg (PE), for easy detection trematode eggs from fecal samples in endemic areas of clonorchiasis and metagonimiasis in Korea. To create a...
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Genetic structure of apical membrane antigen-1 in Plasmodium falciparum isolates from Pakistan

Zaib K, Khan A, Khan MU, Ullah I, Võ TC, Kang JM, Lê HG, Na BK, Afridi SG

Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a major candidate for the blood-stage malaria vaccine. Genetic polymorphisms of global pfama-1suggest that the genetic diversity of the gene can disturb effective...
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Alterations in immunized antigens of Anisakis pegreffii by ampicillin-induced gut microbiome changes in mice

Kim M, Choi JH, Yi Mh, Oh S, Yong TS, Kim JY

The gut microbiome plays an essential role in host immune responses, including allergic reactions. However, commensal gut microbiota is extremely sensitive to antibiotics and excessive usage can cause microbial dysbiosis....
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Molecular survey of Toxoplasma gondii B1 gene in pigs from various localities in Korea

Kwak D, Seo MG

Toxoplasma gondii, a common protozoan parasite, poses significant public health risks due to its potential to cause toxoplasmosis in humans and can be contracted from pigs, which are considered its...
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Dynamin 2-mediated endocytosis of BLT1 is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products

Lee YA, Shin MH

We previously reported that leukotriene B4 (LTB4) contained in Trichomonas vaginalis-derived secretory products (TvSP) play an essential role in interleukin-8 (IL-8) production in human mast cell line (HMC-1 cells) via...
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The storage mite Tyrophagus putrescentiae induces greater lung inflammation than house dust mites in mice

Kim EM, Kim JY, Kwak YS, Yi MH, Yong TS

Exposure to storage mite (SM) and house dust mite (HDM) allergens is a risk factor for sensitization and asthma development; however, the related immune responses and their pathology have not...
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CysLT receptor-mediated NOX2 activation is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products

Lee YA, Shin MH

Trichomoniasis is caused by a sexually transmitted flagellate protozoan parasite Trichomonas vaginalis. T. vaginalis-derived secretory products (TvSP) contain lipid mediators such as leukotriene B4 (LTB4) and various cysteinyl leukotrienes (CysLTs)...
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Identification of the protease inhibitory domain of Trichinella spiralis novel cystatin (TsCstN)

Yuthithum T, Phuphisut O, Reamtong O, Kosoltanapiwat N, Chaimon S, Kobpornchai P, Thawornkuno C, Malaithong P, Sawatdichaikul O, Adisakwattana P

The Trichinella spiralis novel cystatin (TsCstN) inhibits cathepsin L (CatL) activity and inflammation of macrophages during lipopolysaccharide (LPS) induction. To identify the protease inhibitory region, this study applied an in...
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Population genetic analysis of Plasmodium vivax vir genes in Pakistan

Dinzouna-Boutamba SD, Moon Z, Lee S, Afridi SG, Lê HG, Hong Y, Na BK, Goo YK

Plasmodium vivax variant interspersed repeats (vir) refer to the key protein used for escaping the host immune system. Knowledge in the genetic variation of vir genes can be used for...
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