- Chronic Pancreatitis with Fibrogenesis
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Yoo BM
- KMID: 2168084
- Hanyang Med Rev.
- 2007 Feb;27(1):60-65.
Chronic pancreatitis is an ongoing inflammatory disorder characterized by irreversible destruction of the pancreas associated with disabling chronic pain and permanent loss of exocrine and endocrine function. Fibrosis and loss... -
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- Experimental Models of Pancreatitis
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Hyun JJ, Lee HS
- KMID: 2049015
- Clin Endosc.
- 2014 May;47(3):212-216.
- doi: 10.5946/ce.2014.47.3.212
Acute pancreatitis is an inflammatory disease characterized by interstitial edema, inflammatory cell infiltration, and acinar cell necrosis, depending on its severity. Regardless of the extent of tissue injury, acute pancreatitis... -
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- Etiology, Pathogenesis and Natural Course of Chronic Pancreatitis
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Hyun JJ, Lee HS
- KMID: 2263493
- Korean J Med.
- 2012 Jul;83(1):1-17.
The etiology of chronic pancreatitis varies greatly as demonstrated in the TIGAR-O classification. However, due to the lack of correlation and reproducibility between the etiologic factors and the presentation of... -
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- The Effects of High Glucose, Insulin and TGF-beta 1 on Proliferation and Differentiation of the Pancreatic Stellate Cells
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Hong OK, Kwon HS, Yeom KH, Lee M, Yang JH, Ko SH, Yoo SJ, Son HS, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK
- KMID: 1768000
- J Korean Diabetes Assoc.
- 2003 Jun;27(3):228-240.
BACKGROUND: Although chronic pancreatitis gives rise to fibrosis of pancreatic exocrine tissue, and type 2 diabetes is accompanied by pancreatic fibrosis, the mechanisms of fibrogenesis in the pancreas have been... -
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- Involvement of Nuclear Factor Kappa B in High-Fat Diet-Related Pancreatic Fibrosis in Rats
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Yan MX, Ren HB, Kou Y, Meng M, Li YQ
- KMID: 2053503
- Gut Liver.
- 2012 Jul;6(3):381-387.
BACKGROUND/AIMS: High-fat diets contribute to pancreatic fibrogenesis, but the pathogenesis remains unclear. This study investigated the role of nuclear factor kappa B (NF-kappaB) in high-fat diet-induced pancreatic fibrosis in rats. METHODS:... -
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- Thiazolidinediones on Insulin Resistance and Insulin Secretion in Obese Diabetic OLETF Rats
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Noh JH, Hong SH, Lee KH, Min KM, Yang TY, Lee MS, Kim KW, Lee MK
- KMID: 2008094
- J Korean Diabetes Assoc.
- 2007 Jan;31(1):33-43.
- doi: 10.4093/jkda.2007.31.1.33
BACKGROUND: Thiazolidinediones are synthetic peroxisome proliferator-activated receptor-gamma agonists that decrease insulin resistance but, as in vitro and in vivo studies suggest, may have direct beneficial effects on pancreatic beta cells.... -
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- Pancreatic Stellate Cell Activation by High Glucose and Its Effect on Angiotensin II
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Ko SH, Hong OK, Lee MK, Park EH, Lee SS, Ahn YB, Song KH, Cha BY, Son HY, Kim MJ, Jung IK, Yoon KH
- KMID: 2177758
- J Korean Diabetes Assoc.
- 2005 Jul;29(4):304-314.
BACKGROUND: Pancreatic stellate cells (PSCs) are known to be related to pancreatic inflammation and fibrosis, and are the result of extracellular matrix(ECM) protein synthesis. Recent studies have shown that blockade... -
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- The Effects of Combined Treatment with an HMG-CoA Reductase Inhibitor and PPARgamma Agonist on the Activation of Rat Pancreatic Stellate Cells
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Lee BJ, Lee HS, Kim CD, Jung SW, Seo YS, Kim YS, Jeen YT, Chun HJ, Um SH, Lee SW, Choi JH, Ryu HS
- KMID: 2284274
- Gut Liver.
- 2012 Apr;6(2):262-269.
BACKGROUND/AIMS: Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) and peroxisome proliferator-activated receptor gamma (PPARgamma) ligands can modulate cellular differentiation, proliferation, and apoptosis through various pathways. It has been shown that HMG-CoA... -
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