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Secretory response of cultured acinar cells of rat pancreas to cholecystokinin

Kim H, Kim KH

To determine the adequate models for studying the functions of pancreatic acinar cells, secretory responses to CCK and to CCK receptor antagonist, L-364, 718 were examined in freshly isolated cells...
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The Effects of Methontrexate on the Pancreas of Rats: A Histochemical and Ultrastructural Study

Choi HY, Kim CS, Lee YB

Methonexate is one of the well known anti-cancer chemotherapeutic agents and exerts its action by inhibiting mitoses by inhibition of nucleic acid synthesis. Its effect on actively proliferating normal and...
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Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY

  • KMID: 1093610
  • Exp Mol Med.
  • 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
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