- Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma
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Ye YH, Xin HY, Li JL, Li N, Pan SY, Chen L, Pan JY, Hu ZQ, Wang PC, Luo CB, Sun RQ, Fan J, Zhou J, Zhou ZJ, Zhou SL
- KMID: 2560093
- Clin Mol Hepatol.
- 2024 Oct;30(4):914-928.
- doi: 10.3350/cmh.2024.0296
Background: Intrahepatic cholangiocarcinoma (ICC) is a highly desmoplastic tumor with poor prognosis even after curative resection. We investigated the associations between the composition of the ICC stroma and immune cell... -
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- Biomarkers in pursuit of precision medicine for acute kidney injury: hard to get rid of customs
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Lin KM, Su CC, Chen JY, Pan SY, Chuang MH, Lin CJ, Wu CJ, Pan HC, Wu VC
- KMID: 2557322
- Kidney Res Clin Pract.
- 2024 Jul;43(4):393-405.
- doi: 10.23876/j.krcp.23.284
Traditional acute kidney injury (AKI) classifications, which are centered around semi-anatomical lines, can no longer capture the complexity of AKI. By employing strategies to identify predictive and prognostic enrichment targets,... -
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- Pleotropic effects of hypoxia-inducible factor-prolyl hydroxylase domain inhibitors: are they clinically relevant?
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Chou YH, Pan SY, Lin SL
- KMID: 2540180
- Kidney Res Clin Pract.
- 2023 Jan;42(1):27-38.
- doi: 10.23876/j.krcp.22.118
Anemia is common in patients with chronic kidney disease (CKD) and is mainly caused by insufficient production of erythropoietin from fibrotic kidney. Because anemia impairs quality of life and overall... -
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- Unveiling the enigma of acute kidney disease: predicting prognosis, exploring interventions, and embracing a multidisciplinary approach
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Pan SY, Huang TTM, Jiang ZH, Lin LC, Tsai IJ, Wu TL, Hsu CY, Wang T, Chen HC, Lin YF, Wu VC
- KMID: 2557323
- Kidney Res Clin Pract.
- 2024 Jul;43(4):406-416.
- doi: 10.23876/j.krcp.23.289
Acute kidney disease (AKD) is a critical transitional period between acute kidney injury and chronic kidney disease. The incidence of AKD following acute kidney injury is approximately 33.6%, and it... -
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- Cathepsin D deficiency delays central nervous system myelination by inhibiting proteolipid protein trafficking from late endosome/lysosome to plasma membrane
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Guo DZ, Xiao L, Liu YJ, Shen C, Lou HF, Lv Y, Pan SY
- KMID: 2440052
- Exp Mol Med.
- 2018 Mar;50(3):e457.
- doi: 10.1038/emm.2017.291
This study aimed to investigate the role of cathepsin D (CathD) in central nervous system (CNS) myelination and its possible mechanism. By using CathD knockout mice in conjunction with immunohistochemistry,... -
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- miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy
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Wang F, Lou JF, Cao Y, Shi XH, Wang P, Xu J, Xie EF, Xu T, Sun RH, Rao JY, Huang PW, Pan SY, Wang H
- KMID: 2155654
- Exp Mol Med.
- 2015 May;47(5):e162.
- doi: 10.1038/emm.2015.17
MicroRNAs (miRNAs), a class of small non-coding RNAs, mediate gene expression by either cleaving target mRNAs or inhibiting their translation. They have key roles in the tumorigenesis of several cancers,... -
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