- The anti-nociceptive effect of BPC-157 on the incisional pain model in rats
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Jung YH, Kim H, Kim H, Kim E, Baik J, Kang H
- KMID: 2527601
- J Dent Anesth Pain Med.
- 2022 Apr;22(2):97-105.
- doi: 10.17245/jdapm.2022.22.2.97
Background: The pentadecapeptide BPC-157 has been shown to have anti-inflammatory and wound healing effects on multiple target tissues and organs. Peptides have potent anti-inflammatory effects on periodontal tissues in rats... -
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- Anti-Allodynic Effects of Polydeoxyribonucleotide in an Animal Model of Neuropathic Pain and Complex Regional Pain Syndrome
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Lee SH, Yoo SH, Lee HJ, Han D, Lee J, Jeon SH, Cho EA, Park HJ
- KMID: 2503682
- J Korean Med Sci.
- 2020 Jul;35(26):e225.
- doi: 10.3346/jkms.2020.35.e225
Background: Spinal nerve ligation (SNL) model is one of the representative models of the neuropathic pain model. Neuropathic pain in a chronic post-ischemic pain (CPIP) mimics the symptoms of complex... -
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- Animal Models for Orofacial Neuropathic Pain
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Ahn DK, Park MK
- KMID: 2168187
- Hanyang Med Rev.
- 2011 May;31(2):107-115.
- doi: 10.7599/hmr.2011.31.2.107
Orofacial neuropathic pain is initiated by extraction of teeth or nerve injury from trauma in the trigeminal nerve that innervates the facial area. In the experiment, orofacial neuropathic pain usually... -
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- Effect of intrathecal glycine and related amino acids on the allodynia and hyperalgesic action of strychnine or bicuculline in mice
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Lim ES, Lee IO
- KMID: 2031786
- Korean J Anesthesiol.
- 2010 Jan;58(1):76-86.
- doi: 10.4097/kjae.2010.58.1.76
BACKGROUND: The intrathecal (IT) administration of glycine or GABAA receptor antagonist result in a touch evoked allodynia through disinhibition in the spinal cord. Glycine is an inhibitory neurotransmitter that appears... -
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- Antihyperalgesic Effects of Ethosuximide and Mibefradil, T-type Voltage Activated Calcium Channel Blockers, in a Rat Model of Postoperative Pain
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Shinn HK, Cha YD, Han JU, Yoon JW, Kim BS, Song JH
- KMID: 2278047
- Korean J Pain.
- 2007 Dec;20(2):92-99.
- doi: 10.3344/kjp.2007.20.2.92
BACKGROUND: A correlation between a T-type voltage activated calcium channel (VACC) and pain mechanism has not yet been established. The purpose of this study is to find out the effect... -
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- Alteration of Ionic Zinc Distribution in Rat Spinal Ganglion by Inflammatory Pain Stimulus: Autometallography
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Lee B, Jun G, Kim YS, Lee B, Lee YI, Kim DJ, Jo SM
- KMID: 2224492
- Korean J Anat.
- 2005 Dec;38(6):561-566.
This study was designed to investigate any correlation between the mechanism of pain development and changes of histochemically reactive zinc contents in the rat spinal ganglion following complete Freund's Adjuvant... -
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- Decrease in Zinc Concentration in the Rat Spinal Gray Matter Induced by Peripheral Nerve Ligation, and its Relations with Increased Pain Threshold
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Kim SJ, Choi YH, Yu YC, Lee B, Jo SM
- KMID: 2224499
- Korean J Anat.
- 2004 Aug;37(4):369-375.
This study was designed to investigate any correlation between the mechanism of pain development and changes of histochemically-reactive zinc contents in the rat spinal cords following peripheal nerve ligation. Male... -
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- Neuropathic Pain Model Induced by Electrical Injury of Sciatic Nerve in Rats
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Lee YS, Lee KH, Kim YE, Jung TD, Kim PT
- KMID: 2323654
- J Korean Acad Rehabil Med.
- 2001 Aug;25(4):643-652.
OBJECTIVE: The purpose of this study was to develop a new neuropathic pain model in rat. METHOD: Twenty Sprague-Dawley adult male rats, 10 for control and 10 for experimental, were... -
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- Effects of Intrathecal Magnesium Sulphate in a Rat Model of Postoperative Pain
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Yang NY, Moon DE, Park CM, Lee YK, Park SS, Choi JH, Kim CS, Lee JM, Lee HJ, Kwon OK
- KMID: 2091582
- Korean J Anesthesiol.
- 2000 Dec;39(6):889-899.
- doi: 10.4097/kjae.2000.39.6.889
BACKGROUND: The mechanical hyperalgesia that follows peripheral tissue injury results from peripheral and central sensitization. Central sensitization is initiated and maintained by windup that can be prevented by N-methyl-D-aspartate (NMDA)... -
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- Development of Neuropathic Pain Model with 1% Phenol Injection in Rat Sciatic Nerve
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Lee KH, Lee ZI, Kim YE, Lee YS, Kim PT, Kim MN
- KMID: 2323385
- J Korean Acad Rehabil Med.
- 2000 Apr;24(2):185-192.
OBJECTIVE: The purpose of this study is to develop a new neuropathic pain model in the rat. METHOD: Each male adult rat was anesthetized and the sciatic nerve was exposed. Each... -
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- Introduction of Visceral Pain Model to Test of Visceral Nociception in the Rats
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Lee CW
- KMID: 2104665
- J Korean Pain Soc.
- 1995 Apr;8(1):25-30.
Anlgesic agents against visceral pain typically rely on a noxious chemical irritation of the peritoneum, e. g., acetic acid and phenylquinone writhing test. While useful, this type of assay depends... -
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