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Pain measurement in oral and maxillofacial surgery

Sirintawat N, Sawang K, Chaiyasamut T, Wongsirichat N

Regardless of whether it is acute or chronic, the assessment of pain should be simple and practical. Since the intensity of pain is thought to be one of the primary...
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Performance of Evidence-based Pain Assessment and Management Guidelines among Medical-Surgical Nurses

Kim HL, Song CE, So HS

PURPOSE: This study aimed at the effectiveness to investigate the performance of evidence-based pain assessment and management guidelines. METHODS: Participants were 140 nurses at the med-surgical units. Data were collected in...
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Correlations Between Electrically Quantified Pain Degree, Subjectively Assessed Visual Analogue Scale, and the McGill Pain Questionnaire: A Pilot Study

Kim J, Lee KS, Kong SW, Kim T, Kim MJ, Park SB, Lee KH

OBJECTIVE: To evaluate the clinical utility of the electrically calculated quantitative pain degree (QPD) and to correlate it with subjective assessments of pain degree including a visual analogue scale (VAS)...
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Spinal Noradrenergic Modulation and the Role of the Alpha-2 Receptor in the Antinociceptive Effect of Intrathecal Nefopam in the Formalin Test

Jeong SH, Heo BH, Park SH, Kim WM, Lee HG, Yoon MH, Choi JI

BACKGROUND: Nefopam has shown an analgesic effect on acute pain including postoperative pain. The reuptake of monoamines including serotonin and noradrenaline has been proposed as the mechanism of the analgesic...
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Pain Assessment in Brain Tumor Patients after Elective Craniotomy

Kim YD, Park JH, Yang SH, Kim IS, Hong JT, Sung JH, Son BC, Lee SW

OBJECTIVE: This study was performed to assess the postoperative pain of brain tumor patients who underwent elective craniotomy and to evaluate the factors associated with pain intensity. METHODS: From January 2010...
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GABAB Receptor Modulation on the Antinociception of Intrathecal Sildenafil in the Rat Formalin Test

Kim WM, Yoon MH, Lee HG, Han YG, Kim YO, Huang LJ, Cui JH

BACKGROUND: A phosphodiesterase 5 inhibitor, sildenafil, has been effective against nociception. Several lines of evidence have demonstrated the role of the GABAergic pathway in the modulation of nociception. The impact...
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The Analgesic Effects of Intrathecal Pregabalin in Rat Formalin Tests: Comparison between Pre- and Post-treatment

Cho NR, Kweon TD, Han DW, Yoon KB, Lee YW

BACKGROUND: Pregabalin is an analog of gamma aminobutyric acid, and selectively interacts with the alpha-2-delta subunit of the voltage dependent calcium channels. The aims of this study were to investigate...
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Peripheral Analgesic Effect of Ketamine in Rat Formalin Test

Cho YW, Song SO, Ahn DK, Lee JY

BACKGROUND: This study was performed to compare the analgesic effects of the systemic versus local administration of ketamine and observe the effects of an NMDA receptor agonist on its peripheral...
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The Role of Adrenergic and Cholinergic Receptors on the Antinociception of Intrathecal Zaprinast in the Formalin Test of Rats

Yoon SJ, Kim YO, Huang LJ, Cui JH, Heo BH, Jeong ST, Yoon MH

BACKGROUND: Spinal zaprinast, phospodiesterase inhibitor, has been shown to have an antinociception through an increase of cGMP. The aim of this study was to examine the role of spinal adrenergic...
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The Interaction between Intrathecal NMDA Receptor Antagonist and 5-HT3 Receptor Agonist in the Rat Formalin Test

Han DW, Kweon TD, Lee JS, Yoo YC, Lee YW, Kim SC

BACKGROUND: A single agent administered is not effective enough to block nociception. Combination of agents acting through different mechanisms may be one of the best ways for better analgesic methods....
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Evaluation of Pain Assessment Education Program for Nurses

Lee JK

  • KMID: 2291574
  • J Korean Acad Adult Nurs.
  • 2007 Mar;19(1):66-77.
PURPOSE: This study was performed to evaluate the effectiveness of a pain assessment education program developed for nurses. METHODS: Research design of this study was nonequivalent control group quasi-experimental study....
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The Antinociceptive Effect of Intraperitoneally Administered Nonselective Nitric Oxide Synthase Inhibitor on the Rat Formalin Test

Oh M, Lee W, Go Y

BACKGROUND: Nitric oxide (NO) is involved in the transmission and modulation of nociceptive information at the peripheral, spinal cord and supraspinal levels. We conducted this experiment to assess the...
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Effects of Naloxone on Morphine Analgesia and Spinal c-fos Expression in Rat Formalin Test

Song SO, Seok JH, Lee DH, Park DP, Kim SY, Lim JS, Song SK, Lee NH

BACKGROUND: This study was performed to evaluate the dose-related effects of naloxone on morphine analgesia in the rat formalin test, and observe the correlation of pain behavior and spinal c-fos...
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Antinociceptive Effect of the Intrathecal Phosphodiesterase Inhibitor, Zaprinast, in a Rat Formalin Test

Heo BY, Kim CM, Jeong ST, Kim SJ, Choi JI, Yoon MH

BACKGROUND: Cyclic guanosine monophosphate (cGMP) and opioid receptors are involved in the modulation of nociception. Although the opioid receptors agonists are active in pain, the effect of an phospodiesterase inhibitor...
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Analysis of Interaction between Intrathecal Gabapentin with MK801, 5,7-DKA or NBQX in the Rat Formalin Test

Kim MK, Ki HG, Choi JI, Yoon MH, Jeong CY

  • KMID: 2274924
  • Chonnam Med J.
  • 2005 Aug;41(2):200-208.
Spinal NMDA receptor and AMPA receptor are involved in the modulation of nociceptive transmission. It has been known that the antinociception of gabapentin is linked to these sites. We evaluated...
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Effect of Partial Sciatic Nerve Injury on the Response to Formalin Test in Rats

Yu SB, Kim HK, Lee HJ, Shin SW, Baik SW

BACKGROUND: Different types of injury to the sciatic nerve branches produces different levels of each kind of nociception. In this study, we undertook to identify the nature of the...
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Effects of Intrathecal Flecainide for Pain Behavior in Formalin Test and Hemodynamics in Rat

Park HC, Kim CM, Choi JI, Jeong SW, Bae HB, Park GD, Yoon MH

BACKGROUND: The antinociceptive activity of drugs with a sodium channel blocker is an anti-arrhythmic agent belonging to the Ic class. Although the antinociceptive effects of flecainide have been demonstrated in...
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Antinociceptive Effects of Intrathecal Adenosine Receptors Subtype Agonists in the Formalin Test

Yoon MH, Bae HB, Park HC, Choi JC, Choi JI

BACKGROUND: Adenosine has shown an antinociceptive action, which is mediated via spinal adenosine receptors. Previous studies have revealed the presence of four subtypes of adenosine receptor, A1, A2A, A2B and...
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Evaluation of the Interaction between Intrathecal 5-Hydroxytryptamine and Adenosine in the Formalin Test in a Rat Model

Yoon MH, Bae HB, Choi JI

BACKGROUND: Spinal 5-hydroxytryptamine (5-HT) and adenosine have been shown to display an antinociceptive effect. The authors evaluated the characteristics of this drug interaction after the concurrent delivery of 5-HT and...
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The Effects of Gabapentin on Facial Formalin Test

Kim CH, Baik SW, Kim HK, Kwon JY, Kim KH, Choi SH

BACKGROUND: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect...
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