- Effects of Caloric Restriction on the Expression of PGC-1 and PPARs mRNA in Liver of Otsuka Long-Evans Tokushima Fatty Rats
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Kim SY, Kim JH, Bae HY, Lee BR
- KMID: 2177607
- J Korean Diabetes Assoc.
- 2006 May;30(3):161-169.
- doi: 10.4093/jkda.2006.30.3.161
BACKGROUND: Gluconeogenesis is strongly stimulated during fasting and is aberrantly activated in diabetes mellitus. PPARgamma-coactivator 1 (PGC-1) and Peroxisome proliferator -activated receptors (PPARs) costimulate the expression of key enzymes of... -
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- Fenofibrate, a peroxisome proliferator-activated receptor alpha-agonist, blocks lipopolysaccharide-induced inflammatory pathways in mouse liver
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Won TW
- KMID: 1472524
- Korean J Hepatobiliary Pancreat Surg.
- 2013 Aug;17(3):89-108.
- doi: 10.14701/kjhbps.2013.17.3.89
BACKGROUNDS/AIMS: During the acute phase response, cytokines induce marked alterations in lipid metabolism including an increase in serum triglyceride levels and a decrease in hepatic fatty acid oxidation, in bile... -
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- PPARgamma Agonist Beyond Glucose Lowering Effect
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Sugawara A, Uruno A, Kudo M, Matsuda K, Yang CW, Ito S
- KMID: 1036145
- Korean J Intern Med.
- 2011 Mar;26(1):19-24.
- doi: 10.3904/kjim.2011.26.1.19
The nuclear hormone receptor PPARgamma is activated by several agonists, including members of the thiazolidinedione group of insulin sensitizers. Pleiotropic beneficial effects of these agonists, independent of their blood glucose-lowering... -
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