- Association between air pollution in the 2015 winter in South Korea and population size, car emissions, industrial activity, and fossil-fuel power plants: an ecological study
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Choi H, Myong JP
- KMID: 2428626
- Ann Occup Environ Med.
- 2018 ;30(1):60.
- doi: 10.1186/s40557-018-0273-5
BACKGROUND: Compared to 10Â years ago, the ambient particulate matter 10 (PM10) and carbon monoxide (CO) levels in South Korea have decreased. However, compared to many other OECD countries, these levels... -
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- Spatial analysis between particulate matter and emergency room visits for conjunctivitis and keratitis
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Lee JY, Kim JW, Kim EJ, Lee MY, Nam CW, Chung IS
- KMID: 2428607
- Ann Occup Environ Med.
- 2018 ;30(1):41.
- doi: 10.1186/s40557-018-0252-x
BACKGROUND: The concentration of particulate matter in the air varies depending on the region because it is lightweight and generated from a variety of sources. To assess the relationship between... -
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- Outdoor Air Pollution and Pterygium in Korea
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Lee KW, Choi YH, Hwang SH, Paik HJ, Kim MK, Wee WR, Kim DH
- KMID: 2417597
- J Korean Med Sci.
- 2017 Jan;32(1):143-150.
- doi: 10.3346/jkms.2017.32.1.143
We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey... -
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- Effect of Phorbol 12-Myristate 13-Acetate on the Differentiation of Adipose-Derived Stromal Cells from Different Subcutaneous Adipose Tissue Depots
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Song JK, Lee CH, Hwang SM, Joo BS, Lee SY, Jung JS
- KMID: 2285522
- Korean J Physiol Pharmacol.
- 2014 Aug;18(4):289-296.
- doi: 10.4196/kjpp.2014.18.4.289
Human adipose-tissue-derived stromal cells (hADSCs) are abundant in adipose tissue and can differentiate into multi-lineage cell types, including adipocytes, osteoblasts, and chondrocytes. In order to define the optimal harvest site... -
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- Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-alpha and IL-6 Release by Blockading NF-kappaB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187
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Lu Y, Jeong YT, Li X, Kim MJ, Park PH, Hwang SL, Son JK, Chang HW
- KMID: 2170660
- Biomol Ther.
- 2013 Nov;21(6):435-441.
Emodin, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, has several beneficial pharmacologic effects, which include anti-cancer, anti-diabetic, and anti-inflammatory activities. In this study, the authors examined the... -
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- Differential Physiological Effects of Raf-1 Kinase Pathways Linked to Protein Kinase C Activation Depending on the Stimulus in v-H-ras-transformed Cells
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Lee M
- KMID: 2166000
- Cancer Res Treat.
- 2008 Jun;40(2):39-44.
PURPOSE: We investigated the molecular mechanism by which the Raf-1 kinase pathways that are linked to protein kinase C induce differential physiological effects, depending on the stimulus, by employing the... -
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- Expression of Human Melanocyte Markers in PMA-containing Medium and Physiologic Mitogen-containing Medium
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Yoon TJ, Kim KT, Kim KH, Lee JW, Lee MH
- KMID: 2248994
- Korean J Dermatol.
- 2006 May;44(5):579-585.
BACKGROUND: There are many growth media for cultivation of human melanocytes (MGM), depending on the supplements added, and the growth of cells is closely related to these components. To understand... -
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- Down-regulation of Membrane Bound CD27 Expression Mediated by Protein Kinase C-beta and Protein Kinase C-delta in B Cells
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Lee SY, Min JK, Cho ML, Moon YM, Kim KW, Min SY, Cho YG, Yoon CH, Park SH, Kim HY
- KMID: 2202281
- J Korean Rheum Assoc.
- 2006 Mar;13(1):33-45.
OBJECTIVE: CD27 is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on T, B, and NK cells. The signaling via CD27 plays pivotal roles in... -
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- Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-gamma
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Lee KJ, Kim HA, Kim PH, Lee HS, Ma KR, Park JH, Kim DJ, Hahn JH
- KMID: 1103320
- Exp Mol Med.
- 2004 Dec;36(6):534-544.
During chronic inflammatory response, mono- cytes/macrophages produce 92-kDa matrix metalloproteinase-9 (MMP-9), which may contribute to their extravasation, migration and tissue remodeling. Activation of peroxisome proliferator- activated factor receptor-gamma (PPAR-gamma) has... -
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- Expressional Regulation of Cancer Metastasis Related Gene, MMP-9, by Resveratrol
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Woo JH, Kim YH, Baek WK, Suh SI, Suh MH, Park JW, Kwon TK
- KMID: 1615505
- J Bacteriol Virol.
- 2003 Sep;33(3):235-243.
Proteolytic degradation of the extracellular matrix and tumor metastasis correlate with the expression of endopeptidases known as matrix metalloproteinases (MMPs). Expression of MMPs is regulated by cytokines and signal transduction... -
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- Effect of Age on Proliferation of Rat Vascular Smooth Muscle Cells Stimulated with Fetal Bovine Serum, Angiotensin II and Phorbol 12-Myristate 13-Acetate
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Han HS
- KMID: 2092787
- Korean J Anat.
- 2002 Jun;35(3):201-210.
The present study investigated effects of fetal bovine serum (FBS), angiotensin II (Ang II) and phorbol 12 -myristate 13 -acetate (PMA) on proliferation of vascular smooth muscle cells (VSMC)... -
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- Cell-type specific regulation of thrombospondin-1 expression and its promoter activity by regulatory agents
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Kim SA, Kang JH, Cho IH, Bae SW, Hong KJ
- KMID: 938874
- Exp Mol Med.
- 2001 Sep;33(3):117-123.
Thrombospondin-1 (TSP-1), a multifunctional protein that is able to function as a negative regulator of solid tumor progression and angiogenesis, is normally present at a very low level but rapidly... -
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- Responsive site on the thrombospondin-1 promotor to down-regulation by phorbol 12-myristate 13-acetate in porcine aortic endothelial cells
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Kim SA, Hong KJ
- KMID: 755077
- Exp Mol Med.
- 2000 Sep;32(3):135-140.
Thrombospondin-1 (TSP-1), a multifunctional extracellular matrix protein, inhibits neovascularization and is implicated in the regression of tumor growth and metastasis. We found that the synthesis of TSP-1 in... -
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- A Case of Common Variable Immunodeficiency with Autoimmune Hemolytic Anemia
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Lee KY, Lee YJ, Cha SW, Han JW, Whang KT, Kim JG
- KMID: 1946282
- J Korean Pediatr Soc.
- 2000 Jan;43(1):117-122.
Common variable immunodeficiency (CVID) is a heterogeneous collection of disorders with hypogammaglobulinemia with recurrent bacterial infections and high incidence of autoimmune disorders as its hallmark. We report a 7-year-old girl... -
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- Effects of protein kinase C modulation on hepatic hemodynamics and glucoregulation
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Lee JW, Kong ID, Park KS, Chung HS, Filkins JP
- KMID: 2071560
- Korean J Physiol Pharmacol.
- 1999 Dec;3(6):571-578.
This study evaluated the effects of PKC activation using phorbol 12-myristate 13-acetate (PMA) and PKC inhibition using the isoquinoline sulfomide derivative H-7 on hemodynamics and glucoregulation in the isolated perfused rat liver. Livers... -
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- Inhibition of Interleukin-1 Signal by Annexin-1 in Phorbol Myristate Acetate Stimulated Lymphocytes
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Rhee HJ, Park KK, Na DS, Kim HW
- KMID: 1550785
- Korean J Immunol.
- 1999 Jun;21(2):147-152.
Annexin-1 (ANX1) is a 37 kDa protein that is induced and secreted by glucocorticosteroid hormone. The secreted ANX1 has been believed to exert its function by binding to its putative... -
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- Comparison of the human melanocyte culture in phorbol 12-myristate 13-acetate-contained medium and physiologic mitogens-contained medium
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Lee MH, Ryou JH, Jubh BJ
- KMID: 2086189
- Korean J Dermatol.
- 1999 Feb;37(2):168-176.
BACKGROUND: The growth of cells is closely related to components in a culture medium. There are many reports about cellular characteristics of melanocytes grown in a PMA-contained medium. However, only... -
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- Isolation and Characterization of Tumor Cell - Derived Immunoregulatory Factors
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Lim JH, Kim HJ, Jo EK, Yoon WH, Paik TH, Park JK
- KMID: 2083013
- Korean J Immunol.
- 1998 Mar;20(1):39-46.
It has been known that the immunological functions against cancer cells were diminished, and these phenomena result from the inhibition of cell-mediated immunity by substance(s) secreted from cancer cells. It... -
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- The Role of Protein Kinase C in Acute Lung Injury Induced by Endotoxin
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Kim YH, Moon SH, Kim HT, Kee SY, Ju JH, Park TE, Im KI, Cheong SW, Park CS, Jin BW
- KMID: 2049998
- Tuberc Respir Dis.
- 1997 Apr;44(2):349-359.
- doi: 10.4046/trd.1997.44.2.349
BACKGROUND: The signal pathways and their precise roles for acute respiratory distress syndrome caused by endotoxin (ETX) has not been established. Since there has been several in vitro experiments suggesting... -
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