Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

39 results
Display

Determination of Repeat Numbers of (CA)n in Mitochondrial D-loop using Polymerase Chain Reaction-single Strand Conformational Polymorphism (PCR-SSCP)

Kim JY, Kim DK

Polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) analysis is a kind of sensitive mutation detection method that has been usually used in field of medical genetics. A single DNA strand...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
p53 Mutation and p53 Protein Expression in Gastric Cancer Tissues

Ku KB, Park SH, Chung HY, Yu W, Lee MH

  • KMID: 2211067
  • J Korean Surg Soc.
  • 2007 Apr;72(4):283-289.
PURPOSE: Variable changes occur in the progression from normal gastric epithelium to cancer, including many tumor, tumor suppressor and DNA repair genes, as well as growth factor and its receptors....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparision of PCR-RFLP, PCR-SSCP, Amplication Refractory Mutation System (ARMS) in Leu72Met Polymorphism of Ghrelin Gene

Kang JS, Kim SR, Kim SY, Joo CU, Cho SC, Hwang PH

  • KMID: 2279065
  • Korean J Pediatr.
  • 2005 Oct;48(10):1068-1075.
PURPOSE: The role of ghrelin, which promotes the secretion of growth hormone, was not well known until now. Recently it was found that the mutation of ghrelin gene is related...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Property of p53 Gene in Cell Lines of Squamous Cell Carcinoma

Jin Y, Moon YS, Jeong HS, Jang SI, Choi IJ

  • KMID: 2224509
  • Korean J Anat.
  • 2004 Jun;37(3):293-299.
The mutation of p53 tumor suppressor gene is the most common genetic variation of primary malignant tumors. The occurrence, progression and reaction for medical management of cancers can be different...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Study on the expression and detection of the p53 mutation in Korean colon cancer cell lines

Jung JY, Oh SJ

BACKGROUND: Inactivation in p53 tumor suppressor gene through a point mutation and deletion is one of the most frequent genetic changes found in human cancer, with 50% of an incidence....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Topographic expression of p21WAF1/SDI1/CIP1, bcl2, and p53 is altered at the early stage of colorectal carcinogenesis

Cho JH, Roe IH, Lim CY, Park DK, Kim WH, Kim YI

We analyzed the expression of p21, bcl2, and p53 in normal and different pathologic mucosa of the human colorectum using immunohistochemistry and cold polymerase chain reaction-single strand conformation polymorphism. The topography...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Molecular variants of the FSH receptor exon 10 (Thr307Ala; A919G) in premature ovarian failure (POF) women by PCR-SSCP

Kim NK, Lee SH, Nam YS, Sohn TJ, Park SH, Park C, Ko JJ, Cha KY

  • KMID: 2262030
  • Korean J Obstet Gynecol.
  • 2000 Jul;43(7):1144-1146.
OBJECTIVE: This study was performed to determine whether the FSH receptor mutation is present in infertile Korean patients with 46,XX premature ovarian failure (POF) women. METHODS: The variant of FSH receptor...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Two Case Reports of Spinal Muscular Atrophy(SMA) Confirmed by Molecular Genetic Studies

Woo HY, Choi KM, Lee MH, Kim BJ, Kim HS, Kim JW

  • KMID: 2225956
  • Korean J Clin Pathol.
  • 2000 Jun;20(3):342-348.
We present two cases of the patients with spinal muscular atrophy(SMA) confirmed by molecular genetic studies. The first one is 1-year-old female child with SMA type II(Dubowitz disease) who visited...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer

Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY

  • KMID: 1109306
  • Exp Mol Med.
  • 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of Mycobacterium avium complex ( MAC ) clinical Strains to a Species Level by Sequencing and PCR - SSCP Analysis of rpoB DNA

Kim BJ, Lee SH, Lee KH, Park CK, Choi MS, Kim IS, Choi SB, Hwang ES, Cha CY, Kim SJ, Bai GH, Kook YH

  • KMID: 1543612
  • J Korean Soc Microbiol.
  • 1999 Oct;34(5):491-500.
A recent study showed that comparative sequence analysis of rpoB DNAs could reveal natural relationships in genus Mycobacterium [J Clin Microbiol. 37 (6). 1999]. rpoB DNAs showed interspecies variation and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Sequencing of p53 Gene Mutations in Primary Breast Cancer Tissues

Bae JW, Koo BH, Whang CW, Park SH, Kim IS

  • KMID: 2329160
  • J Korean Cancer Assoc.
  • 1999 Aug;31(4):663-669.
PURPOSE: The etiology of breast cancer involves very complex factors such as genetic, hormonal, and dietary. The peak age of Korean breast cancer is much earlier, about ten years, than...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Case of Glucose-6-phosphate dehydrogenase Riley Causing Hemolytic Anemia

Park SW, Lee HJ, Lee W, Whang KT

  • KMID: 2083383
  • Korean J Hematol.
  • 1999 May;34(2):334-337.
A glucose-6-phoshate dehydrogenase variant called G6PD Riley was detected in an Korean boy with nonspherocytic hemolytic anemia. Using polymerase chain reaction based single-strand conformation polymorphism (PCR-SSCP) followed by DNA sequence...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Comparative Study of the Detection of the p53 Abnormality in Breast Cancer by Using PCR-SSCP and Antibody Staining

Bae JW, Lee ES, Cho MY, Koo BH, Whang CW, Kim IS, Park SH, Lee MJ

  • KMID: 2145324
  • J Korean Surg Soc.
  • 1999 Feb;56(2):167-173.
BACKGROUND: Mutations eliminating or altering the p53 protein function are the single most common genetic alteration in nearly all types of human cancers. The project of the p53 gene is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Usefulness of PCR-SSCP for tracing the pathogenesis of human papillomavirus-associated malignancy

Kim JW, Song YS, Park NH, Kang SB, Lee HP

  • KMID: 2244991
  • Korean J Gynecol Oncol Colposc.
  • 1998 Dec;9(4):445-452.
PURPOSE: To set up more simplified detection method for human papillomavirus (HPV) sequence polymorphism which could be used for the study of HPV-related pathogenesis, route of infection, and many...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
p53 Mutation in Gastric Carcinoma Detected by PCR - SSCP and Direct - Sequencing

Lee SS, Kim SP, Sohn EJ, Hwang MS, Sohn SS

  • KMID: 2175300
  • J Korean Cancer Assoc.
  • 1998 Dec;30(6):1069-1077.
PURPOSE: p53 gene mutations, one of the most common alterations found in human tumors, has also been detected in gastric carcinoma, and shown to have a crucial and early role...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A Study of the p53 Tumor Suppressor Gene Mutations in Hepatocellular Carcinomas in Korean Patients

Jeong JH, Lee KS, Cho YH

  • KMID: 2095427
  • J Korean Surg Soc.
  • 1998 Nov;55(5):726-736.
BACKGROUND: Hepatocellular carcinoma is the second most common cause of death among cancers in Korea. Epidemiological studies have revealed the carrier state of the hepatitis B virus and the dietary...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mutation of The p53 Gene in Acute Myelogenous Leukemia

Jung CW, Lee SJ, Kim WS, Ahn MJ, Chung TJ, Kim IS, Choi LY, Kim SY, Yoon HJ, Cho KS, Kim BK, Lee YY

  • KMID: 1849135
  • Korean J Hematol.
  • 1998 Oct;33(3):303-310.
BACKGROUND: A p53 gene is one of the member of tumor suppressor genes involved in the control of cell cycle. The alteration of the p53 gene induces uncontrolled cellular proliferation...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Study of CDKN2/p16INK4A Mutation in Human Breast Cancer

Song TJ, Lee ES, Kwon JA, Kim CS, Bae JW, Koo BH

  • KMID: 2005574
  • J Korean Surg Soc.
  • 1998 Aug;55(2):167-175.
The p16 is a cyclin-dependent kinase inhibitor(CDKI) that inhibits cell cycle progression. In recent studies, homozygous deletions of p16 gene have been noted in some cancer cell lines, which implies...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Heterogeneous HBV mutants coexist in Korean hepatitis B patients

Keum WK, Kim JY, Kim JY, Chi SG, Hong JW, Kim SS, Ha JH, Kang IS

  • KMID: 754997
  • Exp Mol Med.
  • 1998 Jun;30(2):115-122.
Although many hepatitis B virus (HBV) mutants have been found in all open reading frames since the precore defective mutant was initially reported, systematic investigations of diverse HBV mutant populations in hepatitis...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers

Kim JR, Kim SY, Kim MJ, Kim JH

  • KMID: 754996
  • Exp Mol Med.
  • 1998 Jun;30(2):109-114.
The CDKN2 (MTS1/p16INK4A) gene, encoding cyclin dependent kinase inhibitor, was found to be homozygously deleted at a high frequency in cell lines from many different types of cancer and some primary cancers....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr