- Molecular characterisation of pancreatic zymogen granule ion channel and regulator proteins involved in exocytosis
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Thevenod F, Braun M, Roussa E, Fuller CM
- KMID: 1026951
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S51-S52.
- doi: 10.3346/jkms.2000.15.S.S51
In pancreatic acinar cells Ca(2+)-dependent secretagogues promote the fusion of zymogen granules (ZG) with the apical plasma membrane (PM) and exocytosis of digestive enzymes. In addition to exocytotic fusion complexes... -
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- Multi-drug resistance (MDR1) gene expression in de novo acute leukemia cells: correlations with CD surface markers and treatment outcome
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Jiang EZ, Chang YJ, Lee JW, Lee WK, Kim JS, Sohn SK, Lee KB, Suh JS
- KMID: 1038442
- J Korean Med Sci.
- 1998 Dec;13(6):617-622.
- doi: 10.3346/jkms.1998.13.6.617
One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the... -
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- Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells
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Kim SH, Yeo GS, Lim YS, Kang CD, Kim CM, Chung BS
- KMID: 754993
- Exp Mol Med.
- 1998 Jun;30(2):87-92.
MDR1 promoter has been shown to contain heat shock elements (HSE), and it has been reported that FM3A/M and P388/M MDR cells show a constitutively activated heat shock factor (HSF), suggesting that... -
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- Treatment Outcome of Multidrug Resistance Related mRNA Expression and c-Jun-N-Terminal Kinase Activity in Patients with Acute Myeloid Leukemia
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Do JH, Oh SH, Song EJ, Chung JS, Kang CD, Lee EY
- KMID: 1781489
- Korean J Lab Med.
- 2007 Aug;27(4):229-236.
- doi: 10.3343/kjlm.2007.27.4.229
BACKGROUND: The multidrug resistance (mdr1), multidrug resistance associated protein (mrp1), and glutathione-s-transferase (gst) pi genes have been associated with treatment failure in acute myeloid leukemia (AML). c-jun N-terminal kinase... -
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