- SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation
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Gagliardi , Llambi S, Arruga MV
- KMID: 2344299
- J Vet Sci.
- 2015 Sep;16(3):273-280.
- doi: 10.4142/jvs.2015.16.3.273
The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which... -
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- Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability
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Lee W, Choi HI, Kim MJ, Park SY
- KMID: 1103594
- Exp Mol Med.
- 2008 Feb;40(1):109-117.
- doi: 10.3858/emm.2008.40.1.109
The mutation and reduction of mitochondrial DNA (mtDNA) have been suggested as factors in the carcinogenesis. However, whether the depletion of mtDNA induces multidrug resistance in cancer cells has not... -
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