- NLRP1-Mediated Antidepressant Effect of Ketamine in ChronicUnpredictable Mild Stress Model in Rats
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Aricioğlu F, Yalcinkaya C, Ozkartal C, Tuzun E, Sirvanci S, Kucukali C, Utkan T
- KMID: 2500233
- Psychiatry Investig.
- 2020 Apr;17(4):283-291.
- doi: 10.30773/pi.2019.0189
Objective NOD-like receptor protein 1 (NLRP1) inflammasome complex has been recently associated with chronic unpredictable mild stress (CUMS) model of depression. Our aim was to investigate whether ketamine-induced antidepressant effect is... -
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- Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats
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Aricioglu , Ozkartal C, Bastaskin , Tüzün E, Kandemir C, Sirvanci S, Kucukali C, Utkan T
- KMID: 2456729
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):261-272.
- doi: 10.9758/cpn.2019.17.2.261
OBJECTIVE: Purinergic 2X7 receptor (P2X7R) activation is known to be involved in pathogenesis of depression. Our aims were to investigate P2X7R-activated inflammasome pathways in parallel with induction of depression and... -
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