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Enhanced expression of cathepsin L in metastatic bone tumors

Park IC, Lee SY, Jeon DG, Lee JS, Hwang CS, Hwang YG, Lee SH, Hong WS, Hong SI

Cathepsin L is a kind of cystein proteases which are known to facilitate the invasion and metastasis of tumor cells by degrading the components of basement membrane and extracellular matrix....
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Long Non-Coding RNA TUG1 Promotes Proliferation and Inhibits Apoptosis of Osteosarcoma Cells by Sponging miR-132-3p and Upregulating SOX4 Expression

Li G, Liu K, Du X

PURPOSE: Long non-coding RNA taurine upregulated gene 1 (TUG1) is reported to be a vital regulator of the progression of various cancers. This study aimed to explore the exact roles...
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Current state-of-the-art in human cell transformation in culture

Rhim JS

The immortalization and transformation of cultured human cells has far-reaching implications for both cell and cancer biology. Human cell transformation studies will increase our understanding of the mechanisms underlying carcinogenesis...
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Sec13 induces genomic instability in U2OS cells

Sihn CR, Suh EJ, Lee KH, Kim SH

  • KMID: 1056239
  • Exp Mol Med.
  • 2005 Jun;37(3):255-260.
Sec13p has been known as an endoplasmic reticulum-Golgi transport protein. Recently, it has also been shown to be required for the formation of septation in the fission yeast Schizosaccharomyces pombe....
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