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Expression of Osteoprotegerin and RANK Ligand in Breast Cancer Bone Metastasis

Park HR, Min SK, Cho HD, Kim DH, Shin HS, Park YE

Bone destruction is primarily mediated by osteoclastic bone resorption, and cancer cells stimulate the formation and activation of osteoclasts next to metastatic foci. Accumulating evidences indicate that receptor activator of...
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IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice

Park MJ, Park HS, Oh HJ, Lim JY, Yoon BY, Kim HY, Cho ML, Cho SG

  • KMID: 1401761
  • Exp Mol Med.
  • 2012 Nov;44(11):694-705.
IL-17-producing CD4+ T cells (Th17) play important functions in autoimmune diseases and allograft rejection of solid organs. We examined the effects of IL 17 and its mechanism of action on...
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