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Efficacy of the extract of Brachypodium sylvaticum as a preventive and an improving agent of periodontal disease

Moon SH, Son JL, Shin SJ, Oh S, Kim SH, Bae JM

We evaluated the antibacterial, anti-inflammatory, and inhibitory effect of osteoclast differentiation of Brachypodium sylvaticum (BS) to find out the possibility of preventing periodontal disease. The inhibition of Porphyromonas gingivalis (P....
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Inhibition of Osteoclast differentiation based on precipitation time of titanium surfaces immersed in modified simulated body fluid

Chang HM, Heo SJ, Kim SK, Koak JY

PURPOSE: The purpose of this study is to investigate the changes of osteoclast differentiation inhibition according to the period of precipitation when titanium disks were immersed in Modified simulated body...
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Regulation of Osteoclast Differentiation by Cytokine Networks

Amarasekara DS, Yun H, Kim S, Lee N, Kim H, Rho J

Cytokines play a pivotal role in maintaining bone homeostasis. Osteoclasts (OCs), the sole bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating factor and receptor activator of NF-κB ligand...
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Inhibition of Osteoclast Differentiation and Bone Resorption by Poria cocos Wolf Extract

Kim JY, Kim JS, Lee SH, Lee MS, Lee CH, Moon SY, Choi MK, Kim JJ, Oh JM, Kwak HB, Cho HJ

  • KMID: 2314126
  • Osteoporosis.
  • 2012 Dec;10(3):136-145.
OBJECTIVES: Osteoclast differentiation and bone resorption are considered a potential therapeutic target to the treatment of erosive bone diseases, including osteoporosis and rheumatoid arthritis. Poria cocos Wolf (PCW), commonly used...
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Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells

Park YR, Eun JS, Choi HJ, Nepal M, Kim DK, Seo SY, Li R, Moon WS, Cho NP, Cho SD, Bae TS, Kim BI, Soh Y

Osteoclasts, derived from multipotent myeloid progenitor cells, play homeostatic roles in skeletal modeling and remodeling, but may also destroy bone in pathological conditions such as osteoporosis and rheumatoid arthritis. Osteoclast...
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Expression of Osteoprotegerin and Osteoclast Differentiation Factor in Human Periodontal Ligament Fibroblast Cells

Rew SH, Heo SR, Kim HS, Oh KO

Recently, soluble TNF receptor homolog osteoprotegerin (OPG) and its membrane-bound ligand osteoclast differentiation factor (ODF) were found to regulate osteoclast formation and function, and bone metabolism. It is now well...
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Effect of 17beta-Estradiol and 1,25-Dihydroxyvitamin D3 on Interleukin-6 Production of Periodontal Ligament Cells

Kwak WA, Choi BK, Lee HJ, Yoo YJ

  • KMID: 2321535
  • J Korean Acad Periodontol.
  • 1999 Sep;29(3):645-653.
Interleukin-6(IL-6) stimulate osteoclast differentiation. 17beta-estradiol, 1,25-dihydroxyvitamin D3(1,25-(OH)2D3) and interleukin-1beta inhibit or stimulate osteoclast differentiation by decreasing or increasing the synthesis of interleukin-6(IL-6) from stromal/osteoblastic cells, respectively. Periodontal ligament(PDL) cells reside...
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Effect of Sonicated Extract of Treponema Denticola on Osteoclast Differentiation

Choi BK, Lee HJ, Jeong GJ, Jung SH, Kwak WA, Yoo YJ

Alveolar bone destruction is a characteristic of periodontal disease. Treponema denticola are found in significantly increased numbers in the sites affected with periodontal disease. In order to clarify the role...
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