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Expression of p53 protein in rheumatoid arthritis synovium. An immunohistochemical analysis

Lee YH, Ji JD, Kim A, Kim CH, Song GG

  • KMID: 759085
  • Korean J Intern Med.
  • 1999 Jan;14(1):59-65.
OBJECTIVES: Mutation of p53 may play a role in manifestation of rheumatoid arthritis synovium, but several studies on p53 expression in synovial tissues of rheumatoid arthritis showed conflicting...
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MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis

Jia J, Feng X, Xu W, Yang S, Zhang Q, Liu X, Feng Y, Dai Z

MicroRNAs (miRNAs) have recently been recognized to have a role in human orthopedic disorders. The objective of our study was to explore the expression profile and biological function of miRNA-17-5p...
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Crosstalk between FLS and chondrocytes is regulated by HIF-2alpha-mediated cytokines in arthritis

Huh YH, Lee G, Song WH, Koh JT, Ryu JH

Rheumatoid arthritis (RA) and osteoarthritis (OA), two common types of arthritis, affect the joints mainly by targeting the synovium and cartilage. Increasing evidence indicates that a significant network connects synovitis...
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