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miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes

Makki MS, Haqqi TM

IL-6 is an inflammatory cytokine and its overexpression plays an important role in osteoarthritis (OA) pathogenesis. Expression of IL-6 is regulated post-transcriptionally by MCPIP1. The 3' untranslated region (UTR) of...
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