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A Tale of Two Fields: Mathematical and Statistical Modeling of Infectious Diseases

Cho HW, Chu C

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A Note on Obesity as Epidemic in Korea

Kim MS, Chu C, Kim Y

Objective To analyze the incidence of obesity in adults aged 19–59 years in Korea and predict its trend in the future. Methods We considered a two-compartmental deterministic mathematical model Susceptible-Infected-Susceptible (SIS), a system...
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Registration of Human Embryonic Stem Cell Lines: Korea, 2010

Lee JY, Lee DY, Choi YS, Lee KJ, Kim YO

In an effort to increase the credibility of human embryonic stem cell (hESC) lines established in Korea, obligatory registration was introduced by the Bioethics and Safety Act 2008, effective as...
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Increased Prevalence of low High-density Lipoprotein Cholesterol (HDL-C) Levels in Korean Adults: Analysis of the Three Korean National Health and Nutrition Examination Surveys (KNHANES 1998–2005)

Choi SJ, Park SH, Park HY

Objectives High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for cardiovascular diseases that has shown a remarkable increase, but little is known about the prevalence of low HDL-C in Korea....
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Ingenol Protects Human T Cells From HIV-1 Infection

Hong KJ, Lee HS, Kim Ys, Kim SS

Objectives Many natural compounds have been investigated as drug candidates to prevent human immunodeficiency virus (HIV) with low cytotoxicity. We tested whether ingenol from Euphorbia ingens exerts anti-HIV effects in human T...
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Modeling for Estimating Influenza Patients from ILI Surveillance Data in Korea

Lee JS, Park SH, Moon JW, Lee J, Park YG, Roh YK

Objective Prediction of influenza incidence among outpatients from an influenza surveillance system is important for public influenza strategy. Methods We developed two influenza prediction models through influenza surveillance data of the Korea Centers...
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Improved HPLC Method Using 2,3-naphthalenedicarboxaldehyde as Fluorescent Labeling Agent for Quantification of Histamine in Human Immunoglobulin Preparations

Kim JH, Shin IS, Lee YK, Oh HJ, Ban SJ

Objectives To develop and optimize quantitative HPLC method using 2,3-naphthalenedicarboxaldehyde (NDA) after simple and efficient solid phase extraction to determine the histamine in a biopharmaceutical (Histobulin™). Methods The HPLC method was established using...
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Estimation of HIV Seroprevalence in Colorectal Hospitals by Questionnaire Survey in Korea, 2002–2007

Kee MK, Hwang DY, Lee JK, Kim SH, Chu C, Lee JH, Kim SS

Objectives The incidence of anal disease is higher among persons with human immunodeficiency virus (HIV) infection than among the general population. We surveyed the status of seroprevalence in colorectal hospitals in...
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Plasma Calcium and Risk of Hypertension: Propensity Score Analysis Using Data From the Korean Genome and Epidemiology Study

Kim JW, Ko KP, Koo HJ, Ahn Y, Park SJ, Kim HM, Kim Y, Kim SS

Objective To investigate associations between plasma calcium and future incidence of hypertension in a healthy population. Methods We used prospective data from Ansung and Ansan cohorts (n = 10,038) of the Korean Genome and Epidemiology...
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Multilocus Sequence Analysis of Housekeeping Genes and Antigenic Determinant Genes in Bordetella pertussis Strains Isolated in Korea

Jung SO, Moon YM, Kim SH, Sung HY, Kwon SJ, Kang YH, Yu JY

Objectives To confirm genotype diversities of clinical isolates of Bordetella pertussis and to evaluate the risk of pertussis outbreak in Korea. Methods Seven housekeeping genes and 10 antigenic determinant genes from clinical B....
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Development of a Predictive Model for Type 2 Diabetes Mellitus Using Genetic and Clinical Data

Lee J, Keam B, Jang EJ, Park MS, Lee JY, Kim DB, Lee CH, Kim T, Oh B, Park HJ, Kwack KB, Chu C, Kim HL

Objectives Recent genetic association studies have provided convincing evidence that several novel loci and single nucleotide polymorphisms (SNPs) are associated with the risk of developing type 2 diabetes mellitus (T2DM). The...
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