- Lamivudine and adefovir combination therapy in lamivudine-resistant HBeAg-positive chronic hepatitis B patients
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Lee HC
- KMID: 2305780
- Korean J Med.
- 2009 Dec;77(6):713-715.
The introduction of lamivudine (LAM) has opened a new era for the treatment of chronic hepatitis B (CHB). However, the major drawback of LAM, which currently limits its use as... -
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- Intravesical Cidofovir in the Treatment of Hemorrhagic Cystitis after Unrelated Cord Blood Transplantation
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Yoon H, Kim JE, Park JS, Lee JG, Shin DK, Oh D, Chong SY
- KMID: 2264125
- Korean J Med.
- 2011 Nov;81(5):663-666.
Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report a case of hemorrhagic cystitis after unrelated cord blood transplantation associated with adenovirus infection. Despite hydration,... -
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- Serial Follow-up of White Matter Connectivity in a Patient with Progressive Multifocal Leukoencephalopathy Presenting Clinical Improvement
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Chung DI, Oh SI, Oh KP, Baek W, Kim HJ, Kim SH
- KMID: 1966481
- J Korean Neurol Assoc.
- 2011 Nov;29(4):347-351.
Progressive multifocal leukoencephalopathy (PML) is a fatal disease that is characterized by progressive demyelination of the cerebral white matter due to JC viral infection. We report serial magnetic resonance spectroscopy... -
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- The recent trend of prenatal screening
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Hwang D
- KMID: 2184441
- J Genet Med.
- 2008 Jun;5(1):7-14.
Twenty years have passed since a prenatal screening for Down syndrome and neural tube defect was applied to obstetric field. The Quad test (AFP, hCG, uE3, Inhibin-A) of the second... -
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- Frequently used antiviral agents in the clinical environment
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Han S, Yim DS
- KMID: 2190715
- J Korean Med Assoc.
- 2011 May;54(5):530-536.
- doi: 10.5124/jkma.2011.54.5.530
More than 60 antiviral agents for various infectious diseases such as herpes, hepatitis, influenza, and AIDS are currently prescribed worldwide. Among the viral infections, hepatitis B and influenza are those... -
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- A Case of Combining Intravenous Immunoglobulin and Leflunomide for BK Nephropathy
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Cho SY, Bae JM, Nam WJ, Kim JG, Kim SH, Oh DJ, Yu SH
- KMID: 2263746
- Korean J Med.
- 2011 Oct;81(4):512-516.
BK virus nephropathy has emerged as an important cause of renal allograft dysfunction. It affects 1-10% of renal transplant patients and results in significant graft dysfunction in more than 50%... -
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- Strategy to Overcome Drug Resistance That Develops during Treatment of Chronic Hepatitis B in Children
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Hong SJ, Choe BH
- KMID: 2315322
- Pediatr Gastroenterol Hepatol Nutr.
- 2012 Jun;15(2):63-73.
Development of antiviral resistance to lamivudine is the most important factor for the treatment failure. It is necessary to establish proper guidelines to overcome drug resistance for children with chronic... -
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- Treatment of chronic hepatitis B
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Shin JW, Park NH
- KMID: 2258427
- Korean J Med.
- 2009 Sep;77(3):265-274.
Despite the introduction of hepatitis B virus (HBV) vaccine for over 20 years now, HBV infection remains an important health problem. Antiviral treatment of chronic hepatitis B has dramatically changed... -
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- Options for the management of antiviral resistance during hepatitis B therapy: reflections on battles over a decade
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Yim HJ, Hwang SG
- KMID: 1705199
- Clin Mol Hepatol.
- 2013 Sep;19(3):195-209.
- doi: 10.3350/cmh.2013.19.3.195
Although much advancement has been achieved in the treatment of chronic hepatitis B, antiviral resistance is still a challenging issue. Previous generation antiviral agents have already developed resistance in a... -
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- Long Term Effects of Lamivudine and Adefovir dipivoxil in Chronic Hepatitis B Patients on the Development of Hepatocellular Carcinoma
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Lee HJ
- KMID: 2320112
- Yeungnam Univ J Med.
- 2008 Jun;25(1):1-18.
Although Lamivudine and adefovir dipivoxil are efficacious drugs for preventing hepatocellular carcinoma (HCC) in chronic hepatitis B patients, their efficacy is far from completely satisfactory. The risk of liver cirrhosis... -
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- Experience with Entecavir Therapy for Lamivudine-Resistant Chronic Hepatitis B in Korean Children and Adolescents
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Cho SM, Choe BH, Chu MA, Kim JM
- KMID: 1459443
- Korean J Pediatr Gastroenterol Nutr.
- 2010 Mar;13(1):44-50.
- doi: 10.5223/kjpgn.2010.13.1.44
PURPOSE: To estimate the viral suppressive effect of entecavir monotherapy in Korean children and adolescents with lamivudine-resistant chronic hepatitis B (CHB). METHODS: One milligram of entecavir was administered once daily to... -
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- A case of hypophosphatemic osteomalacia associated with low-dose adefovir dipivoxil treatment
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Yoo KD, Jeong JH, Cho SK, Kim GH, Choi HS, Kim DS, Jun JB
- KMID: 2142948
- Korean J Med.
- 2010 Feb;78(2):261-265.
Adefovir dipivoxil (ADV) effectively inhibits lamivudine-resistant hepatitis B virus replication. Hypophosphatemia and elevated serum creatinine are ADV-related nephrotoxicity caused by high-dose ADV. Hypophosphatemic osteomalacia is very rare and is induced... -
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- The association between adverse pregnancy outcomes and the serum inhibin A levels in mid-trimester of gestation
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Oh HM, Kim SY, Lee SP, Sohn YK, Lee GH, Kim JM
- KMID: 2273518
- Korean J Obstet Gynecol.
- 2008 Nov;51(11):1239-1244.
OBJECTIVES: To investigate the association between abnormal inhibin-A level in Quad test during the 15 and 18 weeks of gestation and adverse pregnancy outcomes. METHODS: From January 2005 to March 2007,... -
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- Pathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B
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Lee YS, Kim BK, Lee HJ, Dan J
- KMID: 2412353
- Clin Orthop Surg.
- 2016 Jun;8(2):232-236.
- doi: 10.4055/cios.2016.8.2.232
In Fanconi syndrome, hypophosphatemic osteomalacia is caused by proximal renal tubule dysfunction which leads to impaired reabsorption of amino acids, glucose, urate, and phosphate. We present a rare case of... -
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- A Case of Intravesical Cidofovir Treatment of BK Virus-Associated Hemorrhagic Cystitis after Allogeneic Peripheral Blood Stem Cell Transplantation
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Kang SH, Lee HJ, Jang YS, Ji JH, Lee SA, Lee WS, Lee JL, Lee KH
- KMID: 1469812
- Yeungnam Univ J Med.
- 2009 Dec;26(2):143-147.
- doi: 10.12701/yujm.2009.26.2.143
Hemorrhagic cystitis (HC) is a common complication after allogeneic transplantation. Early posttransplant HC occurs in association with cyclophosphamide, while later on HC results from viral infections such as polyomavirus BK... -
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- Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient
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Jung YK, Yeon JE, Choi JH, Kim CH, Jung ES, Kim JH, Park JJ, Kim JS, Bak YT, Byun KS
- KMID: 1974143
- Gut Liver.
- 2010 Sep;4(3):389-393.
Adefovir dipivoxil (ADV) is commonly used as an antiviral agent in the treatment of chronic hepatitis B or human immunodeficiency virus infection. Nephrotoxicity has been shown to occur at daily... -
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- Management of Antiviral Resistance in Chronic Hepatitis B
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Lim YS
- KMID: 2412184
- Gut Liver.
- 2017 Mar;11(2):189-195.
- doi: 10.5009/gnl15562
The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint... -
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- Post-Marketing Surveillance for the Safety and Effectiveness of Adefovir in Patients with Chronic Hepatitis B
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Shin KY, Choi HM, Oh SY, Kim JH, Lee YS, Kweon YO
- KMID: 2334501
- J Korean Soc Clin Pharmacol Ther.
- 2011 Dec;19(2):180-191.
BACKGROUND: To investigate the safety and effectiveness of adefovir in Korean patients with chronic hepatitis B, an observational study was carried out. METHODS: A total of 4,393 patients with chronic hepatitis... -
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- Quasispecies and Pre-Existing Drug-Resistant Mutations of Hepatitis B Virus in Patients with Chronic Hepatitis B
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Kim DY, Chang HY, Lim SM, Kim SU, Park JY, Kim JK, Lee KS, Han KH, Chon CY, Ahn SH
- KMID: 1431351
- Gut Liver.
- 2013 May;7(3):329-334.
- doi: 10.5009/gnl.2013.7.3.329
BACKGROUND/AIMS: To investigate pre-existing hepatitis B virus (HBV) quasispecies and the genotypic evolution of several variants. METHODS: From six patients with lamivudine (LAM) failure, serum samples at pretreatment, 6 months of... -
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- Treatment of transverse deficiency with surgically assisted rapid palatal expansion in an open bite patient showing pseudomacroglossia
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Kim YJ, Lee KH, Park JW, Rhee GJ, Cho HJ, Park YH
- KMID: 2190259
- J Korean Assoc Oral Maxillofac Surg.
- 2008 Jun;34(3):376-382.
Anterior open bite is a condition in which maxillary and mandibular incisors do not occlude at central occlusion. It is a vertical discrepancy of the jaws and dental arches... -
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