- Benzylideneacetophenone derivatives attenuate IFN-gamma-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition
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Lee SH, Lim SY, Choi JH, Jung JC, Oh S, Kook KH, Choi YH
- KMID: 2155365
- Exp Mol Med.
- 2014 Jun;46(6):e100.
- doi: 10.1038/emm.2014.26
The aim of the present study was to identify a new candidate anti-inflammatory compound for use in the active stage of thyroid-associated ophthalmopathy (TAO). Benzylideneacetophenone compound JC3 [(2E)-3-(4-hydroxy-3-methoxyphenyl)phenylpro-2-en-l-one] was synthesized... -
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