- Reoviral Oncotropism Against c-Myc Overexpressing HS 68 Cells
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Kim M
- KMID: 2149212
- J Bacteriol Virol.
- 2015 Jun;45(2):126-131.
- doi: 10.4167/jbv.2015.45.2.126
Naturally occurring reoviruses are live replication-proficient viruses specifically infecting human cancer cell while sparing normal counterpart. Since the discovery of reoviruses in 1950s, reoviruses have shown various degrees of safety... -
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- Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy
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Kim EJ, Yoo JY, Choi YH, Ahn KJ, Lee JD, Yun CO, Yun M
- KMID: 2158200
- Yonsei Med J.
- 2008 Oct;49(5):811-818.
- doi: 10.3349/ymj.2008.49.5.811
PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression... -
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- Cell Death Mechanisms in Esophageal Squamous Cell Carcinoma Induced by Vesicular Stomatitis Virus Matrix Protein
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Douzandegan Y, Tahamtan A, Gray Z, Nikoo HR, Tabarraei , Moradi A
- KMID: 2456577
- Osong Public Health Res Perspect.
- 2019 Aug;10(4):246-252.
- doi: 10.24171/j.phrp.2019.10.4.08
OBJECTIVES: Vesicular stomatitis virus (VSV) is under development as an oncolytic virus due to its preferential replication in cancer cells and oncolytic activity, however the viral components responsible have not... -
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- Combination of Mutated Herpes Simplex Virus (G207) with Radiation for the Treatment of Squamous Cell Carcinoma of the Head and Neck
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Kim SH, Choi EC, Han DH, Han SJ, Kim JH, Nam JI, Kim KM
- KMID: 2276000
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Feb;46(2):139-146.
BACKGROUND AND OBJECTIVES: G207 virus is an ideal candidate of oncolytic viral therapy. It is a multi-gene mutant of HSV-1 with a deletion at the gamma34.5 loci and a LacZ... -
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- Recent Advances and Future Directions in Immunotherapeutics for Hepatocellular Carcinoma
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Cho Y, Han J, Kim W
- KMID: 2448271
- J Liver Cancer.
- 2019 Mar;19(1):1-11.
- doi: 10.17998/jlc.19.1.1
Systemic target therapeutic drugs, such as sorafenib, lenvatinib, or regorafenib are the only drugs that are known to be effective against advanced hepatocellular carcinoma (HCC). However, these agents show a... -
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