- Improved immunodetection of human papillomavirus E7
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Jeon JH, Cho SY, Kim CW, Shin DM, Kwon JC, Choi KH, Kim IG
- KMID: 1121105
- Exp Mol Med.
- 2002 Dec;34(6):496-499.
Human papillomavirus E7 (HPV E7) is a viral oncoprotein that plays an important role in cervical carcinogenesis through binding with retinoblastoma protein (Rb). Inactivation of Rb by E7 is... -
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- E6 Oncoprotein Expression in Non-Small Cell Lung Cancer Patients
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Cho JN, Yoon SY, Hyun DS
- KMID: 2319583
- Tuberc Respir Dis.
- 2011 Nov;71(5):349-354.
BACKGROUND: Lung cancer is the leading cause of cancer deaths in the world. Human papillomavirus (HPV) infection and E6 oncoprotein expression are known risk factors for the development of non-small... -
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- HPV E6 antisense induces apoptosis in CaSki cells via suppression of E6 splicing
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Cho CW, Poo H, Cho YS, Cho MC, Lee KA, Lee SJ, Park SN, Kim IK, Jung YK, Choe YK, Yeom YI, Choe IS, Yoon DY
- KMID: 1081466
- Exp Mol Med.
- 2002 May;34(2):159-166.
Cervical cancer is known to be highly associated with viral oncogene E6 and E7 of human papilloma virus. Down-regulation of oncogene expression by antisense-based gene therapy has been extensively studied.... -
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- Expression and localization of human papillomavirus type 16 E6 and E7 open reading frame proteins in human epidermal keratinocyte
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Kim KH, Yoon DJ, Moon YA, Kim YS
- KMID: 1381212
- Yonsei Med J.
- 1994 Mar;35(1):1-9.
- doi: 10.3349/ymj.1994.35.1.1
Over 60 different types of human papillomavirus (HPV) have been identified, and they are classified into high and low risk groups based on the risk for malignant progression of HPV... -
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- STP-A11, an oncoprotein of Herpesvirus saimiri augments both NF-kappaB and AP-1 transcription activity through TRAF6
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Jeong S, Cho IR, An WG, Jhun BH, Lee BS, Park K, Chung YH
- KMID: 1103681
- Exp Mol Med.
- 2007 Feb;39(1):56-64.
Herpesvirus saimiri (HVS), a member of the gamma-herpesvirus family, encodes an oncoprotein called Saimiri Transforming Protein (STP) which is required for lymphoma induction in non-human primates. However, a detailed mechanism... -
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- The effects of wild type p53 tumor suppressor gene expression on the normal human cervical epithelial cells or human epidermal keratinocytes transformed with human papillomavirus type 16 DNA
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Kim KH, Park TK, Yoon DJ, Kim YS
- KMID: 1123184
- Yonsei Med J.
- 1995 Jun;36(3):287-298.
- doi: 10.3349/ymj.1995.36.3.287
The inactivation of p53 and p105RB by viral proteins or by mutations plays a key role in the oncogenesis of cervical carcinoma. The E6 and E7 proteins of HPV type... -
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- DNA vaccines for cervical cancer: from bench to bedside
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Hung CF, Monie A, Alvarez RD, Wu TC
- KMID: 1091062
- Exp Mol Med.
- 2007 Dec;39(6):679-689.
More than 99% of cervical cancers have been associated with human papillomaviruses (HPVs), particularly HPV type 16. The clear association between HPV infection and cervical cancer indicates that HPV serves... -
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- Characterization of Immortalized Human Corneal Endothelial Cell Line using HPV 16 E6/E7 on Lyophilized Human Amniotic Membrane
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Kim HJ, Ryu YH, Ahn JI, Park JK, Kim JC
- KMID: 1099072
- Korean J Ophthalmol.
- 2006 Mar;20(1):47-54.
- doi: 10.3341/kjo.2006.20.1.47
PURPOSE: To establish the immortalized human corneal endothelial cell line (IHCEn) by transducing human papilloma virus (HPV) 16 E6/E7 oncogenes, and to identify their characteristics when cultivated on a... -
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- Human Papillomavirus 16/18 Expression of Endocervical Glandular Lesions: Relationship with p53 and MIB-1 Expressions
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Yoon HK, Kim YJ, Kang MS
- KMID: 648252
- J Korean Med Sci.
- 2001 Apr;16(2):169-174.
- doi: 10.3346/jkms.2001.16.2.169
The pathogenesis of endocervical glandular lesions are not clearly understood. The aims of this study are to evaluate the etiologic role of human papillomavirus (HPV) 16/18 and the relationship of... -
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- Immunocytochemical detection of HPV16 E7 in cervical smear
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Jeon JH, Shin DM, Cho SY, Song KY, Park NH, Kang HS, Kim YD, Kim IG
- KMID: 1090965
- Exp Mol Med.
- 2007 Oct;39(5):621-628.
Cervical cancer is characterized by a long period of preclinical dysplasia or carcinoma in situ progressing into invasive cancer. Although Papanicolaou (Pap) smear test has contributed significantly to the early... -
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- Human Papilloma Virus Type 16 E7 Genes Protect Astrocytes against Apoptotic and Necrotic Death Induced by Hydrogen Peroxide
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Lee WT, Lee JE, Lee SH, Jang HS, Giffard RG, Park KA
- KMID: 1728868
- Yonsei Med J.
- 2001 Oct;42(5):471-479.
- doi: 10.3349/ymj.2001.42.5.471
Hydrogen peroxide is considered to be a dose- and time-dependent mediator in apoptotic and necrotic death. In this study, we examined the signaling of the E6 and E7 proteins with... -
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