- Toll-like receptor 9 dependent activation of MAPK and NF-kB is required for the CpG ODN-induced matrix metalloproteinase-9 expression
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Lim EJ, Lee SH, Lee JG, Kim JR, Yun SS, Baek SH, Lee C
- KMID: 1094665
- Exp Mol Med.
- 2007 Apr;39(2):239-245.
Unmethylated CpG oligodeoxynucleotides (CpG ODNs) activate immune cells to produce immune mediators. This study demonstrates that in murine macrophage RAW 264.7 cells, CpG ODN-mediated matrix metalloproteinase-9 (MMP-9) expression is regulated... -
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- Down-regulation of ATP-binding cassette transporter G1 expression by unmethylated CpG oligodeoxynucleotides in RAW 264.7 macrophages
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Seo JM, Lee JY, Ji GE, You JC
- KMID: 1022127
- Exp Mol Med.
- 2011 Sep;43(9):510-516.
- doi: 10.3858/emm.2011.43.9.058
We have investigated the effect of various forms of phosphodiester cytidine-phosphate-guanosine oligodeoxynucleotides (CpG ODNs) on the production of pro-inflammatory cytokines and related genes in RAW 264.7 macrophages. Treatment with the... -
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