- Determining NOEL/NOAEL in Repeated-dose Toxicity Studies, When the Low Dose Group Shows Significant Difference in Quantitative Data
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Kobayashi , Pillai KS, Michael M, Cherian KM, Ohnishi M
- KMID: 2312058
- Lab Anim Res.
- 2010 Jun;26(2):133-137.
In repeated-dose 28-day oral toxicity study design, the low dose is fixed as the no observed effect level (NOEL). But, in practice the low dose usually shows significant difference in... -
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