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Modeling of Human Genetic Diseases Via Cellular Reprogramming

Kang MY, Suh JH, Han YM

The generation of induced pluripotent stem cells (iPSCs) derived from patients' somatic cells provides a new paradigm for studying human genetic diseases. Human iPSCs which have similar properties of human...
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Implications and limitations of cellular reprogramming for psychiatric drug development

Tobe BT, Brandel MG, Nye JS, Snyder EY

  • KMID: 2154278
  • Exp Mol Med.
  • 2013 Nov;45(11):e59.
Human-induced pluripotent stem cells (hiPSCs) derived from somatic cells of patients have opened possibilities for in vitro modeling of the physiology of neural (and other) cells in psychiatric disease states....
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