- Use of Molecular Imaging in Clinical Drug Development: a Systematic Review
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Son H, Jang K, Lee H, Kim SE, Kang KW, Lee H
- KMID: 2450011
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):208-215.
- doi: 10.1007/s13139-019-00593-y
BACKGROUND: Molecular imaging such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) can provide the crucial pharmacokinetic-pharmacodynamic information of a drug non-invasively at an early stage of... -
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- Perspectives in Radiomics for Personalized Medicine and Theranostics
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Ha S
- KMID: 2450005
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):164-166.
- doi: 10.1007/s13139-019-00578-x
Radiomics handles imaging biomarker from high-throughput feature extraction through complex pattern recognition that is difficult for human to process. Recent medical paradigms are rapidly changing to personalized medicine, including molecular... -
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- Perspectives for Concepts of Individualized Radionuclide Therapy, Molecular Radiotherapy, and Theranostic Approaches
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Hosono M
- KMID: 2450006
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):167-171.
- doi: 10.1007/s13139-019-00586-x
Radionuclide therapy (RNT) stands on the delivery of radiation to tumors or non-tumor target organs using radiopharmaceuticals that are designed to have specific affinity to targets. RNT is recently called... -
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- Clinical Applications of Technetium-99m Quantitative Single-Photon Emission Computed Tomography/Computed Tomography
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Lee WW, K-SPECT Group
- KMID: 2450007
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):172-181.
- doi: 10.1007/s13139-019-00588-9
Single-photon emission computed tomography/computed tomography (SPECT/CT) is an already established nuclear imaging modality. Co-registration of functional information (SPECT) with anatomical images (CT) paved the way to the wider application of... -
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- Clinical Personal Connectomics Using Hybrid PET/MRI
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Lee DS
- KMID: 2450004
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):153-163.
- doi: 10.1007/s13139-019-00572-3
Brain connectivity can now be studied with topological analysis using persistent homology. It overcame the arbitrariness of thresholding to make binary graphs for comparison between disease and normal control groups.... -
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- Quantitative Imaging of Alpha-Emitting Therapeutic Radiopharmaceuticals
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Seo Y
- KMID: 2450008
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):182-188.
- doi: 10.1007/s13139-019-00589-8
Targeted alpha therapy (TAT) is an active area of drug development as a highly specific and highly potent therapeutic modality that can be applied to many types of late-stage cancers.... -
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- Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by ¹â¸F-FDG PET-CT
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Yoo MY, Koong SS, Kim SW, Kim D
- KMID: 2450014
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):231-234.
- doi: 10.1007/s13139-019-00591-0
A 45-year-old male visited our clinic due to right palmar anhidrosis and contralateral hyperhidrosis. Chest computed tomography (CT) showed a solitary pulmonary nodule with mediastinal lymph node enlargement, but a... -
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- Eruption of Metastatic Paraganglioma After Successful Therapy with ¹â·â·Lu/â¹â°Y-DOTATOC and ¹â·â·Lu-DOTATATE
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Wolf KI, Jha A, van Berkel A, Wild D, Janssen I, Millo CM, Janssen M, Gonzales M, Timmers HJ, Pacak K
- KMID: 2450013
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):223-230.
- doi: 10.1007/s13139-019-00579-w
Metastatic paraganglioma treatment options are limited. Peptide receptor radionuclide therapy (PRRT) has been introduced as a novel management option for metastatic neuroendocrine tumors demonstrating safety, efficacy, and increased quality of... -
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- How Do the More Recent Reconstruction Algorithms Affect the Interpretation Criteria of PET/CT Images?
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Matti A, Lima GM, Pettinato , Pietrobon , Martinelli F, Fanti S
- KMID: 2450012
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):216-222.
- doi: 10.1007/s13139-019-00594-x
PURPOSE: Recently, a new Bayesian Penalized Likelihood (BPL) Reconstruction Algorithm was introduced by GE Healthcare, Q.Clear; it promises to provide better PET image resolution compared to the widely used Ordered... -
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- Lesion-Wise Comparison of Pre-Therapy and Post-Therapy Effective Half-Life of Iodine-131 in Pediatric and Young Adult Patients with Differentiated Thyroid Cancer Undergoing Radioiodine Therapy
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Kumar P, Bal C, Damle NA, Ballal S, Dwivedi SN, Agarwala S
- KMID: 2450010
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):199-207.
- doi: 10.1007/s13139-019-00592-z
PURPOSE: The effective half-life of radioiodine is an important parameter for dosimetry in differentiated thyroid cancer patients, particularly in children. We determined the pre-therapy and post-therapy effective half-life in different... -
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- Development of a Novel Imaging Agent for Determining Albumin Uptake in Solid Tumors
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Daum S, Magnusson , Pes L, Garcia Fernandez J, Chercheja , Medda F, Nollmann F, Koester SD, Perez Galan P, Warnecke A, Abu Ajaj K, Kratz F
- KMID: 2450009
- Nucl Med Mol Imaging.
- 2019 Jun;53(3):189-198.
- doi: 10.1007/s13139-019-00587-w
PURPOSE: The purpose of this study was to investigate the albumin-binding compound 111In-C4-DTPA as an imaging agent for the detection of endogenous albumin accumulation in tumors. METHODS: 111In-C4-DTPA was injected in... -
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