- Prediction of Nuclear Targeting Proteins with Nuclear Localization Signals in Staphylococcus aureus and Nuclear Targeting of beta-lactamase in Host Cells
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Ahn SH, Lee JH, Lee JC
- KMID: 2168702
- J Bacteriol Virol.
- 2015 Mar;45(1):36-43.
- doi: 10.4167/jbv.2015.45.1.36
Nuclear targeting of bacterial proteins in host cells and subsequent interaction with nuclear molecules are an emerging pathogenic mechanism of bacteria. In this study, we predicted the nuclear targeting proteins... -
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- The molecular mechanism for nuclear transport and its application
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Kim YH, Han ME, Oh SO
- KMID: 2451231
- Anat Cell Biol.
- 2017 Jun;50(2):77-85.
- doi: 10.5115/acb.2017.50.2.77
Transportation between the cytoplasm and the nucleoplasm is critical for many physiological and pathophysiological processes including gene expression, signal transduction, and oncogenesis. So, the molecular mechanism for the transportation needs... -
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- A putative pH-dependent nuclear localization signal in the juxtamembrane region of c-Met
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Chaudhary , Cho MG, Nguyen TT, Park KS, Kwon MH, Lee JH
- KMID: 2155384
- Exp Mol Med.
- 2014 Oct;46(10):e119.
- doi: 10.1038/emm.2014.67
The C-terminal fragment of the c-Met receptor tyrosine kinase is present in the nuclei of some cells irrespective of ligand stimulation, but the responsible nuclear localization signal (NLS) has not... -
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- Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
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Choi S, Joo HK, Jeon BH
- KMID: 2164316
- Chonnam Med J.
- 2016 May;52(2):75-80.
- doi: 10.4068/cmj.2016.52.2.75
Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that plays a central role in the cellular response to DNA damage and redox regulation against oxidative stress. APE1/Ref-1 functions in... -
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- Deletion of the Importin-alpha Gene in the Breast Cancer Cell
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Song BJ, Kim CS, Jin MO, Kim DH, Moon YH, Kim IS, Oh ST, Chung SS, Lee JH, Song YT
- KMID: 2095638
- J Korean Surg Soc.
- 1999 Jun;56(Suppl):947-956.
BACKGROUND: BRCA1 (breast-cancer gene 1) is a tumor suppressor gene that accounts for nearly all families of both early onset breast and ovarian cancer and about 45% of families with... -
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