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Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor–Toll-like Receptor 4–Proinflammatory Cytokine Signaling

Nozu T, Okumura T

  • KMID: 2528032
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):173-184.
  • doi: 10.5056/jnm21002
Irritable bowel syndrome (IBS) displays chronic abdominal pain with altered defecation. Most of the patients develop visceral hypersensitivity possibly resulting from impaired gut barrier and altered gut microbiota. We previously...
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