- Periosteal nociceptors induced hypotension and bradycardia under spinal anesthesia: A report of two cases
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Garg R, Karunagaran P, Pawar M
- KMID: 1827999
- Korean J Anesthesiol.
- 2011 Jan;60(1):52-53.
- doi: 10.4097/kjae.2011.60.1.52
The sudden hemodynamic disturbance in the perioperative period can occur because of various surgical and anesthetic reasons but hemodynamic collapse due to noxious stimulus of periosteum stripping has not been... -
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- Adrenergic sensitivity of uninjured C-fiber nociceptors in neuropathic rats
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Nam TS, Yeon DS, Leem JW, Paik KS
- KMID: 1758517
- Yonsei Med J.
- 2000 Apr;41(2):252-257.
- doi: 10.3349/ymj.2000.41.2.252
We investigated the adrenergic sensitivity of afferent fibers in the L4 dorsal roots of rats with a unilateral ligation of the L5-L6 spinal nerves. About 12% of nociceptive fibers on... -
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- Sensitization of Cutaneous Nociceptors in Neuropathic Rats
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Shim B, Gwak YS, Yoon DM, Leem JW, Nam TS, Paik KS
- KMID: 1946654
- J Korean Pain Soc.
- 2002 Jun;15(1):32-42.
BACKGROUND: Peripheral nerve injury leads to neuropathic pain. Although it has been accepted that both peripheral and central processes may play a role in the pathophysiology of these sensory... -
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- Pathophysiology of Pain
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Kim J, Jung SJ
- KMID: 1582524
- J Korean Neurol Assoc.
- 2002 Jan;20(1):1-7.
Pain is a sensation induced by activation of the peripheral nociceptors when tissue is damaged by direct stimuli or has a possibility of damage. There exist nociceptors for detecting the... -
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- Responses of the Nociceptive Axons to the Inflammatory Mediators and Tumor Necrosis Factor-alpha
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Lee JR, Park SC, Leem JG, Bove GM
- KMID: 1936043
- Korean J Anesthesiol.
- 2002 Jul;43(1):114-120.
- doi: 10.4097/kjae.2002.43.1.114
BACKGROUND: Following musculoskeletal injuries, axons are exposed to tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. Exposure of axons to TNF-alpha and complete Freund's adjuvant (CFA) can cause hyperalgesia... -
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- The Effect of Intramuscular Stimulation (IMS) in Cervicogenic Headache
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Kim SS, Park BS, Lee YJ
- KMID: 1936742
- Korean J Anesthesiol.
- 2006 Mar;50(3):355-360.
- doi: 10.4097/kjae.2006.50.3.355
Cervicogenic headache (CGH) is not universally accepted as terminology used to discuss headaches associated with disorders of the cervical spine. Sjaastad was the first to describe CGH that its definition... -
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- Clinical Application of alpha2-delta Ligand
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Shim JH
- KMID: 2168180
- Hanyang Med Rev.
- 2011 May;31(2):55-62.
- doi: 10.7599/hmr.2011.31.2.55
Chronic pathological pain is sustained by mechanisms of peripheral and central sensitization, which are being increasingly investigated at the molecular and cellular levels. The molecular mechanisms of sensitization that occur... -
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- Pulsed Radiofrequency Lesioning of the Medial Branch in a Patient with Cervical Pain Caused by a Metastatic Tumor: A case report
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Lee JH, Ha SH, Kim HT, Park SC, Kwon YE
- KMID: 1936871
- Korean J Anesthesiol.
- 2005 Oct;49(4):590-593.
- doi: 10.4097/kjae.2005.49.4.590
Metastatic spinal tumor may cause pain by direct tumor involvement of bone with activation of local nociceptors or compression of adjacent structures. As an adjunct to pharmacologic therapy, many patients... -
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- Radiofrequency Rhizotomy of the Sacroiliac Joint with S2 Ganglionotomy
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Oh WS, Kang HJ, Kim KM, Kim HS, Lee SC
- KMID: 2298981
- Korean J Anesthesiol.
- 2001 Jan;40(1):117-121.
- doi: 10.4097/kjae.2001.40.1.117
The sacroiliac joint possesses all the characteristics of a true joint and can produce symptoms quite similar to facet joint abnormalities. Pain originating from the sacroiliac joint usually causes... -
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- Pathophysiology of Postherpetic Neuralgia
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Kim C
- KMID: 2199648
- J Korean Pain Soc.
- 2004 Dec;17(Suppl):S13-S16.
- doi: 10.3344/kjp.2004.17.S.S13
Postherpetic neuralgia (PHN) is one of the most extensively investigated neuropathic pains. Much clinical and experimental evidence supports both peripheral and central pathophysiological mechanisms contributing to the pain of PHN.... -
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- Analgesic effect of quetiapine in a mouse model of cancer-induced bone pain
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Heo MH, Kim JY, Hwang I, Ha E, Park KU
- KMID: 2396767
- Korean J Intern Med.
- 2017 Nov;32(6):1069-1074.
- doi: 10.3904/kjim.2015.377
BACKGROUND/AIMS: Cancer-induced bone pain (CIBP) is one of the most common pains in patients with advanced neoplasms. Because of treatment-associated side effects, more than half of cancer patients are reported... -
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- Responses of dorsal horn neurons to peripheral chemical stimulation in the spinal cord of anesthetized cats
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Jung SJ, Park JM, Lee JH, Lee JH, Eun SY, Kim SJ, Lim WI, Cho SH, Kim J
- KMID: 1580631
- Korean J Physiol Pharmacol.
- 2000 Feb;4(1):15-24.
Although nociceptive informations are thought to be processed via different neural mechanisms depending on the types of stimuli, sufficient data have not been accumulated yet. We performed a series of experiments to elucidate... -
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- Capsaicin Blocks the Hyperpolarization-Activated Inward Currents via TRPV1 in the Rat Dorsal Root Ganglion Neurons
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Kwak J
- KMID: 1438552
- Exp Neurobiol.
- 2012 Jun;21(2):75-82.
- doi: 10.5607/en.2012.21.2.75
Capsaicin, the pungent ingredient in hot pepper, activates nociceptors to produce pain and inflammation. However, prolonged exposures of capsaicin will cause desensitization to nociceptive stimuli. Hyperpolarization-activated cation currents (Ih) contribute... -
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- Diagnosis and management of muscle pain
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Kim K, Lee SU
- KMID: 1785380
- J Korean Med Assoc.
- 2013 Feb;56(2):120-126.
- doi: 10.5124/jkma.2013.56.2.120
Muscle pain is one of the most common, as well as elusive, clinical complaints. Pain can be experienced in muscles by any dysfunction of the muscle itself, peripheral nerves, or... -
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- The Role of Protease Activated Receptors and Proteases in Subtly Inflamed Diarrhea-Predominant Irritable Bowel Syndrome
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Jo Y
- KMID: 1711309
- Korean J Gastroenterol.
- 2014 Jan;63(1):59-61.
- doi: 10.4166/kjg.2014.63.1.59
No abstract available. -
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- The Time Course of the Changes in Lactate Produced by Incisions in the Rat
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Cha YD, Lee HS, Han JU, Jung JK, Lee CS, Shin SH, Lim HK, Kim TJ
- KMID: 2104841
- J Korean Pain Soc.
- 2004 Dec;17(2):125-130.
- doi: 10.3344/jkps.2004.17.2.125
BACKGROUND: It is well known that the level of lactate increases in wounds, which is not necessarily caused by a limitation of oxygen delivery, so may not primarily indicate ischemia.... -
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- The Correlation between Perception and Nociception Thresholds by Selected Current Stimuli in Adults
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Kang HC, Kim YI, Hwang KH, Kwak SD, Park W, Kim SY
- KMID: 2032292
- Korean J Anesthesiol.
- 1999 Mar;36(3):474-480.
- doi: 10.4097/kjae.1999.36.3.474
BACKGROUND: This study was designed to investigate the correlation between pain and non-pain sensation of the cutaneous nociceptors in healthy adults use 250 Hz and 5 Hz evoking neuroselective sinusoidal... -
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- Antihyperalgesic Effects of Ethosuximide and Mibefradil, T-type Voltage Activated Calcium Channel Blockers, in a Rat Model of Postoperative Pain
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Shinn HK, Cha YD, Han JU, Yoon JW, Kim BS, Song JH
- KMID: 2278047
- Korean J Pain.
- 2007 Dec;20(2):92-99.
- doi: 10.3344/kjp.2007.20.2.92
BACKGROUND: A correlation between a T-type voltage activated calcium channel (VACC) and pain mechanism has not yet been established. The purpose of this study is to find out the effect... -
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- The Role of the Peripheral Chemokine, CCL3, in Hyperalgesia following Peripheral Nerve Injury in the Rat
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Leem JW, Lee HJ, Nam TS, Yoon DM
- KMID: 1978706
- Korean J Pain.
- 2008 Dec;21(3):187-196.
- doi: 10.3344/kjp.2008.21.3.187
BACKGROUND: Upregulation of one type of the pro-inflammatory chemokine (CCL2) and its receptor (CCR2) following peripheral nerve injury contributes to the induction of neuropathic pain. Here, we examined whether another... -
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- Response to Capsaicin and Changes in Sodium Currents in Dorsal Root Ganglion Neurons of Neuropathic Rats
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Leem JG, Lim TH, Lee JR, Kim JU, Hwang JH, Shin KI
- KMID: 2298940
- Korean J Anesthesiol.
- 1998 Aug;35(2):259-268.
- doi: 10.4097/kjae.1998.35.2.259
BACKGROUND: Allodynia, one of the most debilitating symptoms of neuropathic pain syndromes, can be defined as `pain due to a stimulus that does not normally provoke pain'. Subsets of dorsal... -
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