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Intracellular Loop in the Brain Isoforms of Anoctamin 2 Channels Regulates Calcium-dependent Activation

Lee D, Lim H, Lee J, Ha GE, No KT, Cheong E

  • KMID: 2544625
  • Exp Neurobiol.
  • 2023 Jun;32(3):133-146.
  • doi: 10.5607/en22045
Anoctamin 2 (ANO2 or TMEM16B), a calcium-activated chloride channel (CaCC), performs diverse roles in neurons throughout the central nervous system. In hippocampal neurons, ANO2 narrows action potential width and reduces...
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Assessment of quantitative structure-activity relationship of toxicity prediction models for Korean chemical substance control legislation

Kim KY, Shin SE, No KT

OBJECTIVES: For successful adoption of legislation controlling registration and assessment of chemical substances, it is important to obtain sufficient toxicological experimental evidence and other related information. It is also essential...
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BMD42-2910, a Novel Benzoxazole Derivative, Shows a Potent Anti-prion Activity and Prolongs the Mean Survival in an Animal Model of Prion Disease

Hyeon JW, Noh R, Choi J, Lee SM, Lee YS, An SSA, No KT, Lee J

Prion diseases are a group of neurodegenerative and fatal central nervous system disorders. The pathogenic mechanism involves the conversion of cellular prion protein (PrPC) to an altered scrapie isoform (PrPSc),...
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Expression of Intermediate Filament Proteins in Rat Brain after Cryoinjury

No KT, Hwang KG, Yoo KS

  • KMID: 1468156
  • J Korean Child Neurol Soc.
  • 2009 May;17(1):10-21.
PURPOSE: Traumatic brain injury is a multifaceted injury that involves direct mechanical damage, intraparenchymal and subarachnoid hemorrhage, breakdown of the blood-brain barrier, excitotoxicity, and ischemia. Even though much investigations were...
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