- Ingestion Exposure to Nitrosamines in Chlorinated Drinking Water
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Kim H, Han K
- KMID: 2380153
- Environ Health Toxicol.
- 2011 ;26(1):e2011003.
OBJECTIVES: N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In... -
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- Cytochrome P-450 Dependent Hydroxylation of Chemical Carcinogens
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Hong YS
- KMID: 1969639
- Ewha Med J.
- 1979 Jun;2(2):75-82.
- doi: 10.12771/emj.1979.2.2.75
A large number of chemicals have the ability to induce cancer in a variety of tissues of various hosts, including man. Despite current interest in the viral etiology of a... -
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- Development of Urinary Bladder Pre-Neoplasia by Schistosoma haematobium Eggs and Chemical Carcinogen in Mice
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Chala B, Choi MH, Moon KC, Kim HS, Kwak C, Hong ST
- KMID: 2374799
- Korean J Parasitol.
- 2017 Feb;55(1):21-29.
- doi: 10.3347/kjp.2017.55.1.21
Schistosoma haematobium is a biocarcinogen of human urinary bladder (UB). The present study investigated developing UB cancer mouse model by injecting S. haematobium eggs into the bladder wall and introduction... -
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- Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer
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Niaz K, Maqbool F, Khan F, Bahadar H, Ismail Hassan F, Abdollahi
- KMID: 2406613
- Epidemiol Health.
- 2017;39:e2017009.
- doi: 10.4178/epih.e2017009
Smokeless tobacco consumption, which is widespread throughout the world, leads to oral submucous fibrosis (OSMF), which is a long-lasting and devastating condition of the oral cavity with the potential for... -
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- Effect of Dietary Factors in the Etiology of Stomach Cancer
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Park HS, Kim HS, Choi SY, Chung CK
- KMID: 2304046
- Korean J Epidemiol.
- 1998 Jun;20(1):82-101.
BACKGROUND: Stomach cancer is the most malignant neoplasm among Koreans. There ane a number of epidemiological studies on dietary factors of stomach cancer in many countries. However, analytical studies on... -
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- Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat
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Jang JJ, Cho KJ, Lee YS, Bae JH
- KMID: 1421512
- J Korean Med Sci.
- 1991 Mar;6(1):31-36.
- doi: 10.3346/jkms.1991.6.1.31
The modifying potential of capsaicin (CAP) on lesion development was examined in a rat multiorgan carcinogenesis model. Groups 1 and 2 were treated sequentially with diethylnitrosamine (DEN) (100 mg/kg, ip,... -
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- Fine Structure Alteration of Rat Liver induced by Nitrosohexamethylenamine
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Kim CS, Greenblatt M
- KMID: 687635
- Yonsei Med J.
- 1970 Jun;11(1):31-44.
- doi: 10.3349/ymj.1970.11.1.31
The ultrastructural alterations in rat liver by feeding NHM(nitrosohexamethylenemine). These are described at intervals of 10 days, 5 weeks, 11 weeks, 14 weeks, 19 weeks, and 22 weeks. The group... -
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- Effects of Extremely Low Frequency Elecromagnetic Fields on Thyroid Carcinogenesis Induced by N-bis(2-hydroxypropyl)nitrosamine and Sulfadimethoxine
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Lee SH, Park YJ, Park ES, Kim YS, Choi YS, Kim BG, Park SJ, Chong SM
- KMID: 2004214
- J Korean Surg Soc.
- 2009 Sep;77(3):161-169.
- doi: 10.4174/jkss.2009.77.3.161
PURPOSE: Long-term exposure to extremely low-frequency (60 Hz) electromagnetic fields (ELF-EMF) raises the questions of the induction of biological effects including tumorigenesis. One mechanism through which ELF-MFS could influence neoplastic... -
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- The Production of Micronuclei from Chromosome Aberrations by Chemical Carcinogens in Mice
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Hahn S, Kim DS
- KMID: 687777
- Yonsei Med J.
- 1979 Dec;20(2):105-112.
- doi: 10.3349/ymj.1979.20.2.105
The effect of four alkylating agents (MMS, EMs, DMN, DEM), under various con centrations on mouse bone marrow erythrocytes, were studied by means of the micronucleus test. The results obtained... -
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- B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kappaB, AP-1, Nrf2, and osteopontin
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Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC, Cho MH
- KMID: 1120069
- J Vet Sci.
- 2004 Jun;5(2):131-137.
Toxic effects of ozone, 4-(N-methyl-N-nitrosamino)-1-(3- pyridyl)-1-butanone (NNK), and/or dibutyl phthalate (DBP) were examined through NF-kappaB, AP-1, Nrf2, and osteopontin (OPN) in lungs and livers of B6C3F1 mice. Electrophoretic mobility shift... -
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- Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells
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Moon SH, Kim HW, Kim JS, Park JH, Kim H, Eu GJ, Cho HS, Kang GM, Lee KH, Cho MH
- KMID: 1093633
- J Vet Sci.
- 2004 Dec;5(4):369-378.
Evidences show that eukaryotic mRNAs can perform protein translation through internal ribosome entry sites (IRES). 5'-Untranslated region of the mRNA encoding apoptotic protease-activating factor 1 (Apaf-1) contains IRES, and, thus,... -
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- Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks
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Kim MY, Kim HW, Park JH, Kim JS, Jin H, Moon SH, Eu KJ, Cho HS, Kang G, Kim YS, Kim YC, Kim HY, Lee KH, Cho MH
- KMID: 1093634
- J Vet Sci.
- 2004 Dec;5(4):379-385.
Potential toxicological interactions of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and/or dibuthyl phthalate (DBP) on ozone were investigated after 32- and 52-wk exposures using hprt mutation assay. Male and female B6C3F1 mice exposed to... -
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